摘要
目的 探讨硬膜外分娩镇痛中炎性因子C-反应蛋白（CRP）、白细胞介素-6（IL-6）与产妇产程中体温变化的关系.方法 足月、单胎、头位初产孕妇192例,有分娩镇痛要求者纳入镇痛组（n=94）,无分娩镇痛要求者纳入对照组（n=98）.镇痛组产妇宫口扩张2～3 cm时予硬膜外分娩镇痛,记录所有产妇在入院时、入产房时、宫口扩张2～3cm时及其后每2h耳温;所有产妇产前及产后24 h抽取静脉血检测WBC、CRP和IL-6.结果 镇痛组产妇有7例（9.3％,7/75例）,对照组有4例（5.3％,4/75例）产妇在宫口扩张达3 cm时体温开始上升至38.0～38.3℃,持续至产后4h自行下降,但两组产妇发热率、产程各时点平均体温变化、产前CRP、产前及产后WBC、产前及产后IL-6差异无统计学意义（P＞0.05）;镇痛组产妇产后CRP较对照组高（P＜0.05）.结论 硬膜外分娩镇痛产妇体温变化与感染无关,其发热随产程结束可自行恢复正常.
Objective To investigate the relationship between C-reactive proteins （CRP）,interleukins-6 （IL-6）and the body temperature variation of puerperae underwent epidural labor analgesia.Methods One hundred and ninety-two nulliparous women at full term,monocyesis,head presentation were selected and divided into analgesic group （n=94） and control group （n=98） according to the demand for labor analgesia.After cervix dilated to 2～3 cm,epidural analgesia was executed in analgesic group.All the tympanic temperature after entering the delivery room,the cervix dilated to 2～3cm and every 2 hours afterwards was recorded.Blood samples of all puerperae were taken before and at 24 hours after delivery in order to observe white cell count （WBC）,serum CRP and IL-6.Results The temperature began to rise to 38.0-38.3℃ in 7 cases （9.3%,5/75 cases） in analgesic group and in 4 cases （5.3%,4/75 cases） in control group as the cervical dilated to 3 cm and continued until 4 h postpartum in two groups of maternal,but there was no significant difference in fever rate,temperature variation at every time point,prepartum CRP,prepartum and postpartum W BC and IL-6 in the two groups （P 〉 0.05）;CRP of postpartum in analgesia group was higher than that in the control group （P 〈 0.05）.Conclusion There is no correlation between the temperature variation of those puerperae underwent epidural labor analgesia and infection;the fever could recovered to normal as the labor process was ended.
出处
《实用疼痛学杂志》
2015年第5期333-336,共4页
Pain Clinic Journal
基金
澳门特别行政区科学发展基金资助项目（编号：084/2011/A）
