摘要
不可切除胃癌指患者在疾病初次确诊时病期较晚,无法行根治性手术切除的胃癌.以往临床多采用以姑息化疗为主的综合治疗模式,治疗效果欠佳,患者预后较差.近年来,许多学者通过全身化疗联合放疗、介入、腹腔热灌注化疗等综合治疗手段,将最初不可切除的病例“转化”为能够接受胃癌根治术（D2或D2＋）的病例,显著延长了患者的生存时间,提高了患者生活质量.不可切除胃癌的转化治疗将为部分晚期胃癌患者的综合治疗提供新的外科策略.
The unresectable gastric cancer refers to be unable to accept radical gastrectomy because of advanced stage,which is mainly treated with adjuvant chemotherapy,and obtains only poor prognosis in the past.In recent years,however,some scholars found that the unresectable gastric cancer cases which were treated with systematic chemotherapy,radiochemotherapy,interventional therapy,hyperthermic intraperitoneal peroperative chemotherapy and so on,could be converted into resectable （radical D2 gastrectomy） cases successfully,and their survival time and quality of life are promoted significantly.The conversion therapy for unresectable gastric cancer provides a novel surgical strategy for the comprehensive treatment of part of the advanced gastric cancer patients.
出处
《中华外科杂志》
CAS
CSCD
北大核心
2016年第3期169-171,共3页
Chinese Journal of Surgery
关键词
胃肿瘤
肿瘤辅助疗法
外科手术
Gastric neoplasms
Neoadjuvant therapy
Surgical procedures,operative
