摘要
目的分析山东和广西地区献浆者的血浆白蛋白和IgG含量的差异，以提高血浆利用率。方法将3600份血浆样品按地区、性别、年龄段（18~29、30~40和41～55岁）进行分组，每组100份样品。用AU5400型全自动生化分析仪检测血浆总蛋白、白蛋白和IgG含量，并用单因素方差分析对检测结果进行统计分析。结果单因素方差分析显示，山东与广西地区献浆者间的白蛋白／IgG比值差异具有统计学意义：18～29、30和40和41-55岁男性献浆者F值分别为138．994、186．262和139．056，P值均为0．000；18-29、30-40和41-55岁女性献浆者F值分别为209．670、174．120和155．081，P值均为0．000。山东与广西地区献浆者间的IgG含量差异具有统计学意义：18-29、30-40和41～55岁男性献浆者F值分别为146．756、186．262和195．263，P值均为0．000；18-29、30-40和41～55岁女性献浆者F值分别为186．133、190．365和206．300，P值均为0．000。结论山东和广西地区献浆者的血浆白蛋白和IgG含量存在差异。
Objective To analyze the difference of plasma albumin and IgG contents from donors in Shandong and Guangxi districts to improve the utilization ratio of plasma. Methods Three thousand and six hundred plasma samples were grouped based on region, gender and age （18-29-, 30-40- and 41-55-year-old donors）. The total protein, albumin and IgG contents of plasma were detected by AU5400 automatic biochemical analyzer. The data were analyzed with one-way analysis of variance. Results One- way analysis of variance showed that the difference of albumin/IgG ratio between donors in Shandong and Guangxi districts had statistical significance, F values for 18-29-, 30-40- and 41-55-year-old male donors were 138. 994, 186. 262 and 139. 056 respectively, P values were all 0. 000; F values for 18-29-, 30-40- and 41-55-year-old female donors were 209. 670, 174. 120 and 155. 081 respectively, P values were all 0. 000. The difference of IgG contents between donors in Shandong and Guangxi districts was also statistically significant, F values for 18-29-, 30-40- and 41-55-year-old male donors were 146. 756, 186. 262 and 195. 263 respectively, P values were all 0. 000; F values for 18-29-, 30-40- and 41-55-year-old female donors were 186. 133, 190. 365 and 206. 300 respectively, P values were all 0. 000. Conclusion The plasma albumin and IgG contents between donors in the two districts have difference.
出处
《国际生物制品学杂志》
CAS
2016年第1期20-25,共6页
International Journal of Biologicals
