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Therapeutic Efficacy of Neurostimulation for Depression:Techniques, Current Modalities, and Future Challenges 被引量:8

Therapeutic Efficacy of Neurostimulation for Depression:Techniques, Current Modalities, and Future Challenges
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摘要 Depression is the most prevalent debilitating mental illness; it is characterized as a disorder of mood, cognitive function, and neurovegetative function. About one in ten individuals experience depression at some stage of their lives. Antidepressant drugs are used to reduce the symptoms but relapse occurs in ~ 20% of patients. However, alternate therapies like brain stimulation techniques have shown promising results in this regard. This review covers the brain stimulation techniques electroconvulsive therapy, transcranial direct current stimulation, repetitive transcranial magnetic stimulation, vagus nerve stimulation, and deep brain stimulation, which are used as alternatives to antide- pressant drugs, and elucidates their research and clinical outcomes. Depression is the most prevalent debilitating mental illness; it is characterized as a disorder of mood, cognitive function, and neurovegetative function. About one in ten individuals experience depression at some stage of their lives. Antidepressant drugs are used to reduce the symptoms but relapse occurs in ~ 20% of patients. However, alternate therapies like brain stimulation techniques have shown promising results in this regard. This review covers the brain stimulation techniques electroconvulsive therapy, transcranial direct current stimulation, repetitive transcranial magnetic stimulation, vagus nerve stimulation, and deep brain stimulation, which are used as alternatives to antide- pressant drugs, and elucidates their research and clinical outcomes.
机构地区 Human Systems Lab
出处 《Neuroscience Bulletin》 SCIE CAS CSCD 2016年第1期115-126,共12页 神经科学通报(英文版)
关键词 DEPRESSION Electroconvulsive therapyTranscranial direct current stimulation - Repetitivetranscranial magnetic stimulation ~ Magnetic seizuretherapy . Vagus nerve stimulation. Deep brainstimulation Treatment-resistant depression Depression Electroconvulsive therapyTranscranial direct current stimulation - Repetitivetranscranial magnetic stimulation ~ Magnetic seizuretherapy . Vagus nerve stimulation. Deep brainstimulation Treatment-resistant depression
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