摘要
目的了解大肠癌的临床病理特点及近年来的变化趋势。方法回顾分析我院消化内镜中心2003年1月至2014年12月检出的916例大肠癌的内镜和病理资料。结果 12年来共行结肠镜检查56084例,确诊的大肠癌共916例,检出率为1.63%,平均发病年龄63.3岁,男女比例为1.35:1。直肠是大肠癌的最常见部位,占53.4%;<30岁的患者直肠癌比例最高(66.7%),随年龄增加直肠癌构成比减少,而右半结肠癌增多;高中分化腺癌是大肠癌的主要病理类型,占85.9%,随年龄增加,高中分化腺癌增多,低分化腺癌、印戒细胞癌减少。比较4个3年大肠癌的临床病理特点发现,大肠癌的标化检出率呈下降趋势,直肠癌构成比减少。结论大肠癌检出率较低并呈减少趋势,直肠癌构成比减少;加强对高危人群的筛查和肠镜检查,可提高大肠癌的早期诊断,减少大肠癌的发病率。
Objective To study pathological characteristics and the changing trend in recent years of colorectal cancer.Methods Retrospective analysis was made regarding the results of colonoscopy and pathological examination in patients from January 1990 to December 2004 in digestive endoscopy center of our hospital. Results Totally 56084 patients received colonoscopy during twelve years,and 916 patients were diagnosed as colorectal cancer.The overall diagnostic yield was 1. 63%.The average age diagnosed was 63. 3 years old.Ratio of male to female was 1. 35： 1.The lesion located in rectum accounted for 53. 4%.The proportion（ 66. 7%） of patients with rectal cancer under 30 years old was the highest in all patients with rectal cancer.The proportion of cancer located in left side of the colon increased with age while rectal cancer ratio decreased.Well and moderately differentiated adenocarcinoma was observed in 85. 9% of the patients. Well and moderately differentiated adenocarcinoma increased with age and low differentiated adenocarcinoma and signet- ring cell carcinoma decreased. Comparing the clinicopathological characteristics of every three years,decreasing diagnostic yield was noted,and the proportions of rectal cancer was also decreased.Conclusion The overall diagnostic yield of colorectal cancer was lower and had a decreased trend. The proportion of rectal cancer was decreased.Strengthening the screening and colonoscopy for high-risk groups can improve the early diagnosis of colorectal cancer and reduce the incidence of colorectal cancer.
出处
《四川医学》
CAS
2016年第2期127-131,共5页
Sichuan Medical Journal
基金
上海市卫生和计划生育委员会科研项目(编号:20134171)
上海市松江区科学技术攻关项目(编号:12SJGGYY03)
关键词
大肠癌
结肠镜
病理学
colorectal cancer
colonoscopy
pathology
