摘要
目的分析绝经后阴道出血合并宫颈癌的危险因素。方法将绝经后阴道出血合并宫颈癌患者43例作为观察组;绝经后阴道出血合并非器质性病变及良性病变患者52例作为对照组。通过病历资料和自定的调查表调查绝经后阴道出血合并宫颈癌的危险因素。结果两组的绝经年龄、宫内节育器置入年限、绝经后使用雌激素药物、吸烟史、合并高血压病的差异无统计学意义(t=0.674、1.156,χ2=0.283、0.425、0.281,P>0.05);而观察组的绝经至发生出血的年限、子宫内膜厚度、阴道出血持续时间均大于对照组,差异均有统计学意义(t=6.717、5.000、10.754,均P<0.05)。单因素和多因素Logistic回归分析结果均表明,绝经后阴道出血合并宫颈癌的危险因素为绝经至发生出血的年限、子宫内膜厚度、阴道出血持续时间(均P<0.05)。结论对于绝经后阴道出血患者,应考虑合并宫颈癌的风险,尤其要考虑患者的绝经后至出血的年限、阴道出血持续时间和子宫内膜厚度。
Objective To analyze the risk factors of postmenopausal vaginal bleeding complicating cervical cancer.MethodsTotally 43 cases of postmenopausal vaginal bleeding complicating cervical cancer were selected as the observation group,while 52 cases of postmenopausal vaginal bleeding complicating non-organic lesions and benign lesions were selected as the control group.Through the medical records and self-developed questionnaire,the risk factors of postmenopausal vaginal bleeding complicating cervical cancer were investigated.Results There were no statistically significant differences in age of menopause,age of IUD placement,usage of postmenopausal estrogen drugs,smoking history,complicating hypertension between the two groups（t=0.674,1.156,χ2=0.283,0.425,0.281,P〉0.05）;while the years of menopause to vaginal bleeding occurrence,endometrial thickness and duration of vaginal bleeding in the observation group were more than those in the control group,the differences were statistically significant（t=6.717,5.000,10.754,P〈0.05）.The univariate and multivariate Logistic regression analysis results showed that the risk factors of postmenopausal vaginal bleeding complicating cervical cancer were the years of menopause to bleeding,endometrial thickness and duration of vaginal bleeding（P〈0.05）.Conclusion For the patients with postmenopausal bleeding,the risk of complicating cervical cancer should be considered,especially the years of menopause to bleeding,endometrial thickness and duration of vaginal bleeding.
出处
《重庆医学》
CAS
北大核心
2016年第8期1032-1033,1036,共3页
Chongqing medicine
基金
2014年浙江省医药卫生科技计划项目(2014KYB280)
