摘要
目的探讨早产儿肺透明膜病使用肺泡表面活性物质联合鼻塞式持续气道正压通气(NCAPA)的临床疗效。方法选择2012年1月—2014年5月收治入院的早产儿肺透明膜病患儿40例,随机分为治疗组和对照组各20例,治疗组给予肺泡表面活性物质联合NCAPA治疗,对照组单纯NCAPA治疗,比较2组患儿的临床治疗效果及不良反应情况。结果治疗组患儿总有效率为95%,明显高于对照组的75%,差异有统计学意义(P<0.05);治疗1,12,24h后,治疗组血气分析指标均好于对照组(P<0.05)。结论早产儿肺透明膜病使用肺泡表面活性物质联合NCAPA治疗效果显著,具有一定的临床推广价值。
Objective To investigate the clinical effective of pulmonary surfactant combined with Nasal continuous positive airway pressure in the treatment of Hyaline membrane disease in premature infant.Methods 40 cases with Hyaline membrane disease in premature infant in January 2012- May 2014 were divided into two groups,nasal continuous positive airway pressure was used in control group 20 premature infants. Pulmonary surfactant combined with Nasal continuous positive airway pressure was used in treatment group 20 premature infants and the clinical therapeutic effect and adverse reactions were compared between the two groups.Results The total effective rate of the treament group was 95%,which was significantly higher than of control group（75%）,and the difference was significant（P〈0.05）.Blood gas analysis result was improved markedly at the tine of 1,12,24 hours after treatment in the treatment group;there were significant differences between the two groups（P〈0.05）.Conclusion Pulmonary surfactant combined with Nasal continuous positive airway pressure has a remarkable effect on premature infant with Hyaline membrane disease and it has a certain clinical application value.
出处
《基层医学论坛》
2016年第1期14-16,共3页
The Medical Forum
关键词
早产儿
肺透明膜病
肺泡表面活性物质
鼻塞式持续气道正压通气
Premature infant
Hyaline membrane disease
Pulmonary surfactant
Nasal continuous positive airway pressure
