摘要
目的观察干扰素联合康宁克通预防烧伤瘢痕增生的疗效。方法将所选212例患者按数字表法随机分为观察组和对照组；观察组108例，用干扰素联合康宁克通喷洒创面，对照组104例，创面外用纳米银乳膏；按照温哥华瘢痕量表对各组患者在创面愈合后，分别于3个月、6个月、12个月对各时期瘢痕指标进行评分，并进行统计学处理。结果观察组在监测瘢痕的色素、柔韧性、血管、高度等指标方面，3个月时总有效率96．3％，对照组总有效率51．9％，两组总有效率差异有极显著统计学意义（x^2=58．31，P〈0．01）；6个月时总有效率90．7％，对照组总有效率26．9％，两组总有效率差异有极显著统计学意义（x^2=110．80，P〈0．01）；12个月时总有效率87．0％，对照组总有效率19．2％，两组总有效率差异有极显著统计学意义（x^2=97．99，P〈0．01）。结论干扰素联合康宁克通预防烧伤瘢痕增生具有极显著性疗效，值得推广。
Objective To observe the effect of interferon combined with kenacort in the prevention of burn scar hyperplasia. Methods 212 patients were selected and divided into a treatment group （n=108） and a control group （n=104） by random number table. The treatment group were sprayed the wounds with kenacort and interferon and the control group with nano silver cream. 3, 6, and 12 months after the treatment, both groups were evaluated with Vancouver Scar Scale and the results were statistically analyzed. Results The scar pigmentation, flexibility, blood vessels, height, and other indicators were detected. 3 months after the treatment, the total efficacy was 96.3% in the treatment group and was 51.9% in the the control group, with a statistical difference （x^2 = 58.31, P 〈0.01）; 6 months after the treatment, the total efficacy was 90.7% in the treatment group and was 26.9% in the control group, with a statistical difference（x^2 = 110.80, P 〈0.01）; 12 months after the treatment, the total efficacy was 87.0% in the treatment group and was 19.2% in the control group, with a statistical difference （x^2= 97.99, P 〈0.01）. Conclusions Interferon combined with kenacort in the prevention of burn scar hyperplasia is quite effective and worth being generalized.
出处
《国际医药卫生导报》
2016年第6期821-825,共5页
International Medicine and Health Guidance News
关键词
瘢痕
封闭
动态疗法
Scar
closed
Dynamic therapy
