摘要
目的比较调强放射治疗中4种配对图像获得的放射治疗摆位误差。方法选择2012年南通市第一人民医院住院行放射治疗胸腹部肿瘤患者17例，其中男性12例，女性5例；年龄32～81岁．中位年龄66岁。获取17例胸腹部调强放射治疗患者3组二维（2D）（kv—kv、kv—Mv、Mv—Mv）配对图像和1组三维锥形束CT（3D—CBCT）配对图像，通过根据灰度自动配准及由专业放射治疗医师根据靶区和解剖学结构手动配准．获取摆位误差和临床靶体积（CTV）到计划靶体积（胛V）的预留边界并分析差异。结果3组2D配对图像摆位误差差异有统计学意义．差值在2mm以内。3组2D与3D配对图像摆位误差差异无统计学意义。4组CTV到PTV的预留边界差距在2mm以内。结论4种图像引导方式均能达到临床需要．建议根据设备配置情况灵活选用。
Objective To compare the setup errors obtained from 4 sets of paired images in the thoracic and abdominal tumor radiotherapy. Methods A total of 17 patients with thoracic and abdominal tumor radiotherapy were enrolled, which included 12 males and 5 females, aged 32 - 81 years old with median age of 66 years old. The 3 sets of two-dimensional （2D）（kV-kV, kV-MV, MV-MV） and 1 set of three-dimensional cone beam CT（3D-CBCT） paired images were obtained. The 4 paired im- ages were analyzed by automatic gray paired registration and physician＇s manual registration based on target and anatomy structure respectively, then the setup errors and expanded boundary size from clinical tumor volume （CTV） to planning tumor volume （PTV） were obtained and analyzed. Results The difference of setup errors were found among 3 sets of 2D paired im- ages within 2 mm, there was no difference of setup errors existed between 2D and 3D groups, and the expanded boundary sizes in 4 sets from CTV to PTV were all within 2 mm. Conclusion It is demonstrated that all of 4 sets of paired imageguided setup methods could be used in radiotherapy, so the actual choice is based on the equipment.
出处
《生物医学工程与临床》
CAS
2016年第2期154-156,161,共4页
Biomedical Engineering and Clinical Medicine
基金
南通市社会发展计划基金资助项目(HS2012036)
江苏省六大人才高峰计划基金资助项目(2014-WSN-075)
关键词
锥形束CT
胸腹部肿瘤
放射治疗
摆位误差
cone beam CT（CBCT）
thoracic and abdominal tumor
radiotherapy
setup errors
