摘要
目的通过CT肺功能检查探讨慢性阻塞性肺疾病肺气肿表型患者的临床特征。方法选取2014年1月至2015年10月在我院就诊和住院的稳定期COPD患者66例。行CT行肺功能检查,以密度低于-950Hu判定为肺密度减低区,计算深吸气末低衰减区占全肺容积百分比(LAA%),将LAA%≥15%者分为肺气肿表型组,LAA%<15%者分为非肺气肿表型组。采用CAT量表评价生活质量,记录既往急性加重次数;行常规肺功能检查记录FEV1、FVC、FEV1/FVC、RV/TLC。结果 66例患者平均CAT评分(14.83±7.56)分,平均COPD急性加重次数(2.14±1.42)次,平均FEV1%为(44.94±21.61)%,平均LAA%为(15.25±10.52)%。66例患者中肺气肿组共28例,非肺气肿组共38例,两组患者在年龄、CAT评分、急性加重次数、气流受限方面差异具有统计学意义(P<0.05)。结论 COPD肺气肿表型患者在年龄、急性加重频率、气流阻力、影像学表现及生活质量方面具有其独特性。
Objective To investigate the clinical characteristics of chronic obstructive pulmonary disease patients with pulmonary emphysema by CT pulmonary function test. Method 66 patients with stable COPD-2015 in our hospital from January 2014 to October in our hospital were selected. CT for pulmonary function test, to determine the density of less than-950 Hu reduced lung density, deep inspiratory low attenuation areas total lung volume percentage（LAA%）, LAA% = 15% were divided into the emphysema phenotype were divided into non LAA%15% group and the emphysema phenotype group. CAT was used to evaluate the quality of life, and the number of previous acute exacerbation was recorded, and the routine pulmonary function tests were recorded in FEV1, FVC, FEV1/FVC, RV/TLC. Result The average CAT score was（14.83±7.56）, the average number of COPD was（2.14±1.42）, the average FEV1% was（44.94 ±21.61）, and the average LAA% was（15.25±10.52）. There were 28 cases of emphysema in 66 patients, there were 38 cases of emphysema, the two groups were statistically significant（P〈0.05） in age, CAT score, acute exacerbation and airflow limitation. Conclusion COPD emphysema has its unique characteristics in age, acute exacerbation frequency, airflow resistance, imaging performance and quality of life.
出处
《中国医药指南》
2016年第7期12-13,15,共3页
Guide of China Medicine
关键词
慢性阻塞性肺疾病
CT
肺功能
肺气肿表型
评估
Chronic obstructive pulmonary disease
CT
Pulmonary function
Pulmonary emphysema phenotype
Assessment
