摘要
目的:观察银翘芩百汤治疗小儿支原体肺炎的临床疗效。方法:102例小儿支原体肺炎患儿采取随机数字表法平均分为观察组和对照组。对照组采用常规治疗,观察组联合中医银翘芩百汤进行治疗,比较两组临床疗效。结果:观察组显效30例,有效18例,无效3例;对照组治疗显效18例,有效19例,无效14例;两组有效率比较,差异有统计学意义(P<0.05)。观察组治疗后白细胞计数(7.04±0.51)×10~9L^(-1),C反应蛋白(4.11±1.05)mg·L^(-1);对照组治疗后白细胞计数(9.16±1.02)×10~9L^(-1),C反应蛋白(9.34±1.66)mg·L^(-1);两组比较,差异均有统计学意义(P<0.05)。观察组治疗后白介素-6(13.54±3.19)ng·L^(-1),白介素-10(8.11±2.03)ng·L^(-1),肿瘤坏死因子-α(10.34±2.36)ng·L^(-1);对照组治疗后白介素-6(26.49±4.86)ng·L^(-1),白介素-10(14.31±3.84)ng·L^(-1),肿瘤坏死因子-α(15.18±4.28)ng·L^(-1);两组比较,差异均有统计学意义(P<0.05)。观察组发生转氨酶升高1例,恶心呕吐1例;对照组服药期间发生恶心呕吐1例,头痛1例;两组比较,差异均无统计学意义(P>0.05)。结论:银翘芩百汤治疗小儿支原体肺炎临床疗效可靠,能有效降低患儿机体的炎症反应,改善临床症状和体征。
Objective： To observe the clinical curative effect of Yinqiao Qinbai Tang in treating children mycoplasma pneumonia. Methods： 102 cases of children with mycoplasma pneumonia in children were randomly divided into observation group and control group according to random table method. Control group was given conventional treatment and observation group was given treatment combined with traditional Chinese medicine（ TCM） Yinqiao Qinbai Tang. Compared the clinical curative effect of two groups. Results： In the observation group： 30 cases were markedly effective,18 patients of effectively,3 cases of invalid; In the control group： 18 cases were markedly effective,19 cases of effectively,14 cases of invalid. Compared the efficient of two groups,the difference was statistically significant（ P〈0. 05）. Leukocyte of observation group after treatment was（ 7. 04 ± 0. 51） × 10^9L^-1and C reactive protein was（ 4. 11 ±1. 05） mg·L^-1. Leukocyte of control group after treatment was（ 9. 16 ± 1. 02） × 10^9L^-1and C reactive protein was（ 9. 34 ± 1. 66）mg·L^-1. Compared between the two groups,there had statistical significance（ P〈0. 05）. The IL-6,IL^-10 and TNF-α of treatment group were（ 13. 54 ± 3. 19） ng·L^-1,（ 8. 11 ± 2. 03） ng·L^-1and（ 10. 34 ± 2. 36） ng·L^-1. The IL-6,IL^-10 and TNF-α of control group were（ 26. 49 ± 4. 86） ng·L^-1,（ 14. 31 ± 3. 84） ng·L^-1and（ 15. 18 ± 4. 28） ng·L^-1. Compared between the two groups,there was statistical siguificant difference（ P〈0. 05）. Observation group： 1 case of transaminase rising,1 case of nausea and vomitting,none of headache. Control group： none of transaminase rising,1 case of nausea and vomiting,1 case of headache. Comparison of two groups,there was no statistical siguificant difference（ P〈0. 05）. Conclusion： Yinqiao Qinbai Tang in treating children mycoplasma pneumonia has reliable clinical curative effect,can effectively reduce the body＇s inflammatory response and improve the clinical symptoms and signs.
出处
《中医学报》
CAS
2016年第2期183-186,共4页
Acta Chinese Medicine
基金
河北省卫生厅自然科学项目(201108241)
关键词
银翘芩百汤
小儿支原体肺炎
阿奇霉素
YinqiaoQinbai soup
Children with mycoplasma pneumonia
Azithromycin
