摘要
目的探讨硫酸依替米星联合思密达治疗急性细菌性痢疾的临床疗效。方法选取我院2012年1月至2015年7月期间急性细菌性痢疾患者96例,随机将患者分为两组,各48例,对照组采用硫酸依替米星治疗,观察组在对照组患者的基础上采用思密达治疗,比较两组临床疗效,细菌学疗效、治疗疗程及不良反应率。结果观察组治疗总有效率明显高于对照组,细菌清除率明显高于对照组,两组比较差异具有统计学意义(P<0.05);观察组治疗疗程明显短于对照组,两组比较差异具有统计学意义(P<0.05)。两组患者不良反应率比较差异无统计学意义(P>0.05)。结论硫酸依替米星联合思密达治疗急性细菌性痢疾的临床疗效与细菌学疗效显著,值得临床推广应用。
Objective To investigate the clinical efficacy of etimicin sulfate combined with Smecta in the treatment of acute bacte- rial dysentery. Methods 96 cases of acute bacterial diarrhea were selected in our hospital during January 2012 to July 2015. All pa- tients were randomly divided into two groups, with 48 cases in each group. Patients in control group were treated with etimicin sulfate, while those in observation group were treated with Smecta on the basis of the control group. Clinical efficacy, bacteriological efficacy, therapy sessions and adverse reaction rate were compared between the two groups. Results Total effective rate and bacterial clearance rate of the observation group were significantly higher than those of the control group, the difference between the two groups was statis- tically significant （ P 〈 0. 05 ）. Therapy sessions of the observation group was significantly shorter than that of the control group, the difference between the two groups was statistically significant （ P 〈 0. 05 ）. There was no significant difference in adverse reaction rate between the two groups （ P 〉 0. 05 ）. Conclusion Clinical efficacy and bacteriological efficacy of etimiein sulfate combined with Smecta in the treatment of acute bacterial dysentery are significant, which is worth of clinical application.
出处
《辽宁医学院学报》
CAS
2016年第1期32-34,共3页
Journal of Liaoning Medical University (LNMU) Bimonthly
