摘要
目的通过检测存在胎儿生长受限孕妇的妊娠晚期血清同型半胱氨酸（homocysteine,HCY）水平,研究其与胎儿生长受限的相关性。方法选择2015年3月1日~8月31日期间,在我院住院分娩的63例存在胎儿生长受限的孕妇作为观察组（胎儿生长受限组）,并随机抽取该院同期健康的单胎妊娠晚期孕妇90例作为对照组,对比两组血清HCY水平和临床特征。结果胎儿生长受限组和对照组在孕妇年龄、孕次、产次方面差异无统计学意义（P〉0.05）;两组在分娩孕周、新生儿出生体重、孕妇HCY水平的差异存在统计学意义（P〈0.05）。将胎儿生长受限组按照分娩孕周分为早产组和足月产组后,可见早产组与对照组的HCY水平差异更为显著（P〈0.05）。所有研究对象按照HCY水平分组后可见HCY正常组和异常组的新生儿出生体重的差异也有统计学意义（P〈0.05）。结论妊娠晚期孕妇血清HCY水平与胎儿生长受限存在相关性。
Objective To study its correlation with fetal growth restriction by detecting serum homocysteine（HCY） levels of pregnant women with fetal growth restriction in the third trimester of pregnancy. Methods A total of 63 cases of fetal growth restriction women were recruited as the observation group（FGR group） in our hospital from March 1 to August 31,2015. And randomly selected 90 cases of pregnant women as the control group in the same period. The levels of serum homocysteine and clinical characteristics were compared between the two groups. Results There were no significant differences of maternal age, pregnancies and parities between fetal growth restriction group and control group（P〉0.05）. But the gestational age, birth weight and homocysteine levels had significantly differences between the two groups（P〈0.05）. And the difference of HCY levels between the preterm group with fetal growth restriction and control group was more significant（P〈0.05）. When all the research objects were grouped according to the HCY level, and the difference of birth weight between the HCY normal group and the abnormal group was statistically significant（P 0.05）.Conclusion Serum HCY levels of pregnant women are tightly related to fetal growth restriction, and it requires more clinical attention.
出处
《中国现代医生》
2016年第6期1-3,8,F0003,共5页
China Modern Doctor
基金
浙江省医药卫生科技计划项目(2014KYA208)
