摘要
妊娠期碘营养至关重要,碘能够影响妊娠妇女和胎儿甲状腺功能,进而影响妊娠过程、后代智力和生长发育。严重碘缺乏可导致母亲临床甲状腺功能减退(简称甲减)及胎儿克汀病。在实施普遍食盐加碘计划的地区.妊娠妇女的碘营养可能存在轻中度碘缺乏和碘超足量并存的情况。碘缺乏可导致妊娠妇女单纯低甲状腺素(T4)血症,碘超足量和碘过量可使妊娠妇女亚临床甲减患病危险性升高。给予轻中度碘缺乏的妊娠妇女补充碘剂对甲状腺功能的影响结论不一。因此,妊娠期维持最佳尿碘水平对于预防甲状腺功能异常最为重要。
Iodine is an essential micronutrient for pregnant women, which affects thyroid function of pregnant women and fetus, and thus influences the intellectual development of offspring. Severe iodine deficiency could lead to overt hypothyroidism and fetal cretinism. In the areas implemented the universal salt iodization (USI) program, mild to moderate iodine deficiency and iodine excess may coexist during pregnancy. Iodine deficiency could lead to hypothyroxinemia in pregnant women. Iodine more than adequate and iodine excess could increase the prevalence of subclinical hypothyroidism. The effect of iodine supplementation on thyroid function in pregnant women with mild to moderate iodine deficiency may result in different conclusion. Therefore, it is important to maintain optimal urinary iodine concentration to prevent thyroid dysfunction.
出处
《中华地方病学杂志》
CAS
CSCD
北大核心
2016年第3期161-165,共5页
Chinese Journal of Endemiology
基金
国家科技支撑计划(2014BA106B00)
关键词
妊娠
碘营养
甲状腺功能
Pregnancy
Iodine nutrition
Thyroid function