摘要
支气管哮喘是一种复杂的遗传性疾病，受环境因素影响。表观遗传学作为连接遗传易感因素及环境因素的桥梁，在支气管哮喘发病机制中的作用越来越受到人们的重视。DNA甲基化作为最为常见的表观遗传修饰形式，可受环境及饮食因素的影响，从而对CD4＋T细胞的分化产生影响，促进哮喘的发生。
Bronchial asthma, a complex genetic disease, is influenced by environmental factors. As a connection of genetic susceptibility factors and environmental factors,the role of epigenetics in the pathogenesis of bronchial asthma is attracting more attention. DNA methylation, the most common form of epigenetic modifications, can be influenced by the environment and dietary factors, thereby have an effect on the differentiation of CD4 ＋T lymphocyte, promoting the development of asthma.
出处
《国际儿科学杂志》
2016年第3期177-179,共3页
International Journal of Pediatrics
