摘要
目的探讨磁共振胰胆管造影（MRCP）对于肝移植性胆道并发症的诊断效果。方法检索PubMed、EBSCO、Cochrane Database Systematic Reviews）数据库、CNKI，筛查相关研究文献；运用QUSDAS-2工具对研究对象进行系统评价；提取纳入文献的真、假阳性数，真、假阴性数，进行异质性检测，合并统计量，绘制受试者工作特征曲线（SROC）。结果本研究共纳入文献11篇，纳入文献均表现较高质量，较低偏倚风险和临床适用性风险。合并灵敏度、特异度、阳性似然比、阴性似然比分别为0．96（95％CI：0．94～0，98），0．94（95％CI：0．90～0．97），9．90（95％CI：6．08～16．12），0．06（95％CI：0．03～0．09），257．19（95％CI：117．63～562．30）。SROC下面积为0．98，Q指数为0．9431。结论MRCP对于肝移植性胆道并发症诊断拥有较高灵敏度和特异度，可以作为肝移植性胆道并发症诊断的有效方法。
Objective To determine the diagnostic accuracy of MRCP for biliary tract complications in orthotropic Liver Transplant （OLT） patients. Methods A systematic review and meta-analysis was carried out. Studies comparing MRCP with ERCP PTC surgery were located through electronic searching of the PubMed, EMbase, CNKI, Cochrane library. The methodological quality of included studies was assessed using the QUADAS-2 tool. Data on accuracy of included studies were extracted for further heterogeneity exploring statistical pooling and SROC were analyzed. Results Totally 11 studies met the inclusion criteria. The heterogeneity was found in these studies. The pooled sensitivity, specificity, PLR, NLR and DOR were 0.96（95% CI：0.94 -0,98） ,0.94（95% CI：0.90 -0.97） ,9.90（95% CI：6.08 - 16.12） ,0.06（95% CI：0.03 - 0.09 ） ,257.19 （95% CI ： 117.63 - 562.30） respectively ; The area under of SROC curve was 0.98 and the Q index was 0. 9431. Conclusion The high sensitivity and specificity demonstrated in this meta-analysis suggest that MRCP is a promising test for diagnosing biliary tract complications in orthotropic liver transplant recipients.
出处
《临床放射学杂志》
CSCD
北大核心
2016年第3期404-408,共5页
Journal of Clinical Radiology
