尿微量白蛋白/尿肌酐比值与慢性心力衰竭的关系分析被引量：7

Relationship Analysis between Urinary Albumin/Creatinine Ratio and Chronic Heart Failure

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摘要目的:探讨尿微量白蛋白(MA)和随机尿微量白蛋白/尿肌酐比值(UACR)与慢性充血性心力衰竭(CHF)严重程度关联性,及对心力衰竭预后的评估价值。方法:选取124例CHF患者。比较不同心功能分级患者尿肌酐(Cr)、MA、UACR等指标间差异以及与N端B型利钠肽原(NT-pro BNP)间相关性。比较UACR增高患者和正常患者18个月后各项预后指标差异。结果:MA,UACR等指标在不同心功能组间存在统计学差异(P<0.05),UACR增高组和正常组在各项终点事件发生率上存在统计学差异。结论:MA、UACR能够作为评估CHF患者心功能水平的有效指标,对CHF患者病情评估和预后分析存在重要意义。 [ABSTRACT]Objective: To investigate the correlations between the ratio of urinary albumin(MA) and Urinary albumin/creatinine ratio (UACR) and analyze the value to prognosis in patients with chronic heart failure(CHF). Methods: 124 patients with chronic heart failure enrolled from in-patient were devided into three groups according to NYHA standards.Urinary albumin/creatinine ratio(UACR), MAU, Brain Natriuretic Peptide(BNP), were measured and compared among three groups. Pathological events and cases of death among patients with different UACR were analyzed after a follow-up of 18 months. Results:The differences of UACR and MAU were statistically signiifcant among three groups (P<0.05). Patients with higher UACR suffered higher risks of pathological incidences. Conclusions:The MA and UACR can be a precise indicatrix for monitoring cardical stages and a predictor of pathological incidences in CHF patients.

作者赵汉君葛智儒杜安通王璐

机构地区第二军医大学附属公利医院心内科宁夏医科大学研究生院第二军医大学临床医学院

出处《中国医药导刊》 2016年第3期237-238,240,共3页 Chinese Journal of Medicinal Guide

关键词慢性充血性心力衰竭尿微量白蛋白尿微量白蛋白/尿肌酐比值 N端B型利钠肽原 Chronic heart failure Urinary albumin UACR NT-proBNP

分类号 R541.6 [医药卫生—心血管疾病]

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