摘要
【目的】探讨子宫动脉化疗栓塞联合超声清宫术治疗剖宫产瘢痕妊娠（cesarean scar pregnancy，CSP）的疗效。【方法】收集CSP患者42例，根据患者意愿分为两组：子宫动脉化疗栓塞联合清宫22例为观察组；直接清宫20例为对照组，两者均在超声监视下清宫术。比较两组术中出血量、手术时间长短、术中大出血发生率及并发症。【结果】两组术前年龄、剖宫产次数、流产次数、停经时间、血人体绒膜促性腺激素（HCG）及孕囊直径比较差异均无统计学意义（P〉0．05）。观察组清宫术中出血量10～30mL，均未发生大出血，对照组术中出血量300～2000mL，其中发生大出血8例；观察组出血量及大出血发生率均明显小于对照组（P〈0．01）；观察组手术时间（20．1±10．2）min，显著短于对照组（60．0±10．4）min；观察组有1例发生低热，2例发生下肢或臀部疼痛；对照组1例发热，3例下肢或臀部疼痛，两组不良反应发生率比较无统计学意义（P〉0．05）。【结论】子宫动脉化疗栓塞联合超声清宫术治疗CSP能有效地减少出血量，控制大出血的发生率，缩短手术时间，是CSP的有效治疗方法，值得临床推广应用。
[Objective] To study the efficacy of uterine artery chemoembolization combined with ultrasonic curettage for the treatment of cesarean scar pregnancy （ CSP）.[Methods]Forty-two CSP patients were collected and divided into two groups according to the wishes of patients： 22 cases of uterine artery chemoembolization curettage as the observation group; 20 cases of direct curettage as the control group, both underwent ultrasonic monitoring curettage. The bleeding volume, operation time, the incidence of bleeding and complications were compared between the two groups.[Results] Preoperative indexes like age, times of cesarean section, times of abortion, menopause, blood human chorionic stimulating gonadotropin （hCG） and the gestational sac diameter difference of two groups had no statistical significance （ P 0.05）. The amount of bleeding of uterine curettage of the observation group was 10 - 30 mL, there were no massive bleeding, bleeding of the control group was 300-2000 ml, hemorrhage occurred in 8 cases; Amount of bleeding in the observation group and bleeding incidence was significantly lower than the control group （ P 〈0.01） ;The operation time of the observation group was （20.1 ± 10.2） min, significantly shorter than the control group （60±10.4） rain;In the observation group 1 cases of fever and 2 cases of lower extremity or hip pain occurred;1 case of fever, 3 cases of lower limb or hip pain in the control group , the incidence of adverse reactions in the two groups was not statistically significant （ P 〉0.05）.[Conclusion]Uterine artery chemoembolization combined with ultrasonic curettage for the treatment of CSP can effectively reduce the amount of bleeding and control the incidence of major bleeding, shorten operative time, and is an effective method for the treatment of CSP, which is worth of clinical application.
出处
《医学临床研究》
CAS
2016年第3期519-521,共3页
Journal of Clinical Research
