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紫苏子油对衰老小鼠记忆力和对正常小鼠镇静作用的影响 被引量：7

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摘要 目的探讨紫苏子油对衰老小鼠记忆力的增强作用和对正常小鼠的镇静作用。方法昆明种雌性小鼠,用D-半乳糖建立亚急性衰老模型,随机分为紫苏子油高、中和低剂量组,每组10只,用Morris水迷宫研究紫苏子油对小鼠记忆力的影响,用光电管法测定紫苏子油对小鼠自主活动的影响。结果紫苏子油能缩短衰老小鼠水迷宫登台潜伏期,并随用药时间的延长作用逐渐明显。紫苏子油还能减低正常小鼠的自主活动(即有镇静作用),并无耐受现象。紫苏子油还有对抗中枢神经系统兴奋剂和增强中枢神经系统抑制剂的作用。结论紫苏子油具有增强衰老小鼠记忆力的作用并对正常小鼠有镇静作用。
作者 王亚萍 陈锴 符兆英 秦妮娜 白娜
机构地区 延安大学医学院 延安大学附属医院
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第7期1544-1546,共3页 Chinese Journal of Gerontology
关键词 紫苏子油 记忆力 自主活动 衰老
分类号 R962 [医药卫生—药理学]
  • 相关文献

参考文献15

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二级参考文献25

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共引文献750

同被引文献134

引证文献7

二级引证文献142

中国老年学杂志
2016年 第7期

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