摘要
目的探讨使用纳洛酮治疗脑出血的临床管理疗效。方法选取该院收治的87例脑出血患者作为研究对象,随机分为治疗组44例和对照组43例,所有的87例患者均酌情给予脱水治疗、抗感染、营养神经、调控血压等治疗,治疗组在以上治疗的基础上加用纳洛酮1.2 mg,2次/d静脉滴注,每治疗14 d作为1个疗程,一共观察2个疗程。对比87例患者治疗前后神经功能缺损评分、Glasgow昏迷评分的变化,同时比较两组患者的恢复意识时间。结果治疗组的神经功能缺损评分明显低于对照组,Glasgow昏迷评分明显高于对照组,恢复意识时间比对照组短,治疗组的总有效率为90.91%,明显高于对照组的72.09%,差异有统计学意义(P<0.05)。结论纳洛酮治疗脑出血临床疗效满意,可以改善患者的神经功能缺损程度,促进患者意识的恢复。
Objective To explore the clinical curative effect of naloxone on cerebral hemorrhage. Methods 87 cases patients with cerebral hemorrhage patients in our hospital were selected as the research object, and all patients were randomly divided into treatment group(44 cases) and control group(43 cases), the 87 patients are discretionary given dehydration treatment, anti-infection, nutrition nerves and regulate blood pressure treatment. On the basis of the above treatment,the treatment group combined with 1.2 mg naloxone to treat, 2 times/d intravenous drip, a course of treatment was 14 d, in total2 course. Compared nerve function defect grade and the change of the Glasgow coma scale of 87 patients before and after treatment, at the same time, regained consciousness between the two groups were compared. Results The neural function defect score of treatment group was obviously lower than the control group, and Glasgow coma scale of which was significantly higher than the control group, regain consciousness time shorter than the control group, the total effective rate of treatment group was 90.91%, which was significantly higher than the 72.09% in the control group, the difference was statistically significant(P〈0.05). Conclusion The clinical curative effect of Naloxone in treatment of cerebral hemorrhage was satisfied, which could improve the patient's nerve function defect degree, and promoting the recovery of patients with consciousness.
出处
《中国卫生产业》
2015年第33期166-168,共3页
China Health Industry
关键词
纳洛酮
脑出血
临床管理
Naloxone
Cerebral hemorrhage
Clinical Management