摘要
目的观察支气管舒张剂多索茶碱联合金水宝胶囊治疗慢性阻塞性肺疾病稳定期咳嗽、咳痰、呼吸困难和FEV1近期疗效。方法收集2010年5月～2013年4月收治的86例慢性阻塞性肺疾病（COPD）稳定期患者,将其随机分为两组,两组均接受抗感染、持续低流量吸氧等常规治疗。治疗组43例在此基础上给予多索茶碱联合金水宝胶囊治疗,对照组43例在此基础上给予多索茶碱。两组疗程为12个月,疗程结束后观察咳嗽、咳痰、呼吸困难、FEV1变化情况。结果治疗组和对照组总有效率分别为90.7%和65.12%,两组疗效比较有显著性差异（χ^2=9.434,P=0.008 9）。治疗组FEV1明显升高,对照组FEV1无明显升高,两组差异比较有统计学意义（P〈0.05）。结论多索茶碱联合金水宝胶囊对慢性阻塞性肺疾病稳定期症状、肺功能临床疗效更佳。
Objective Observation of bronchial diastolic agent doxofylline combined with Jinshuibao capsule treatment in patients with stable chronic obstructive pulmonary disease cough,sputum,dyspnea and FEV1 in the near future curative effect. Methods From May 2010 to April 2013,86 patients with stable chronic obstructive pulmonary disease（ COPD） patients were randomly divided into two groups,the two groups were treated with anti infection,continuous low flow oxygen and other conventional treatment. Treatment of group（ 43 cases） was given doxofylline combined with Jinshuibao capsule on the basis of this. Control of group（ 43 cases） was given doxofylline on the basis of this. Two groups of treatment for 12 months,Observation of cough,sputum,dyspnea,FEV1 changes after the end of treatment. Results The total effective rates of the treatment group and the control group were 90. 7% and 65. 12% respectively,and there were significant differences between the two groups（ Χ2= 9. 434,P = 0. 008 9）. FEV1 in treatment group was significantly higher than that in control group,there was no significant increase in FEV1 in the control group,the difference between the two groups was statistically significant（ P〈0. 05）. Conclusions Doxofylline combined with Jinshui Bao Capsule on chronic obstructive pulmonary disease symptoms and lung function clinical curative effect is better.
出处
《航空航天医学杂志》
2016年第3期299-300,共2页
Journal of Aerospace medicine
关键词
多索茶碱
金水宝胶囊
慢性阻塞性肺疾病
肺功能
Doxofylline
Jinshuibao capsule
chronic obstructive pulmonary disease
pulmonary function
