摘要
目的探讨C反应蛋白(CRP)和降钙素原(PCT)对血流感染的诊断价值。方法对217例发热患者根据血培养分为阳性组和阴性组,对所有患者入院当天外周血CRP和PCT进行定量和定性检测,对血培养阳性患者根据病原菌革兰染色分为革兰染色阳性组和革兰染色阴性组,并进行CRP和PCT定量检测。结果阳性组PCT阳性率(99.16%)高于阴性组(30.61%)(P<0.05);阳性组CRP和PCT水平均高于阴性组(P<0.05);革兰阳性组PCT水平(3.48±1.15)ng/ml低于革兰阴性组(7.08±0.67)ng/ml(P<0.05)。结论 CRP和PCT均可作为初步判断血流感染的指标,但PCT具有较高的特异性,且革兰阳性菌感染患者血清PCT水平低于革兰阴性菌感染的患者。
Objective To discuss the value of diagnosis of CRP and PCT in the differential diagnosis of bloodstream infection. Methods 217 cases of fever patients were put into positive group and negative group according to the blood culture. Detection of peripheral blood CRP and PCT levels in all patients. Based on the blood cultures were divided into gram positive and gram negative groups, and then detected the level of CRP and PCT. Results Positive group, the positive rate of PCT（99.16%） is higher than the negative group（30.61%）（P〈0.05）, positive group, the levels of CRP and PCT were higher than those of the negative group（P〈0.05）, leather gram positive serum PCT levels（3.48±1.15） ng/ml below the leather blue negative group（7.08±0.67） ng/ml（P〈0.05）. Conclusion CRP and PCT can be used as an indicator of blood flow infection, but PCT has high specificity, and the level of serum PCT in patients with gram positive bacterial infection was significantly lower than that of gram negative bacteria infection.
出处
《中国继续医学教育》
2016年第7期34-35,共2页
China Continuing Medical Education
关键词
血流感染
C反应蛋白
降钙素原
血培养
革兰染色
Bloodstream infection
C reactive protein
Procalcitonin
Serum procalcitonin
Combined detection
