摘要
目的观察中医补肾益精法联合西医疗法治疗少弱畸精子综合征的临床疗效。方法选取2013年12月至2014年12月郑州市中医院收治的少弱畸精子综合征患者160例为研究对象,采用随机数字表法分为对照组和试验组,各80例。对照组患者给予促卵泡生成激素联合人绒毛膜促性腺激素治疗,其中尿卵泡刺激素75 U,每周3次;人绒毛膜促性腺激素4000 U,每周1次。试验组患者在此基础上口服增精丸6 g,每日3次。3个月为1个疗程,共1个疗程。观察比较两组患者血性激素及男性精子情况。结果试验组患者治疗后精子密度、活率与（a＋b）级精子百分率显著高于对照组[（49±12）×10~9/L比（42±11）×10~9/L,（48±12）%比（43±12）%,（64±12）%比（56±13）%],畸形率显著低于对照组[（22±4）%比（26±6）%],差异有统计学意义（P〈0.05）。试验组患者治疗后血卵泡刺激素、黄体生成素、睾酮水平显著高于对照组[（14.8±1.9）U/L比（12.6±1.7）U/L,（48.6±12.1）U/L比（6.9±1.4）U/L,（21±3）U/L比（19±3）U/L],差异有统计学意义（P〈0.05）。试验组患者治疗后绿色荧光精子百分率显著高于对照组[（69±12）%比（62±13）%],红色荧光精子百分率显著低于对照组[（16±5）%比（22±7）%],差异有统计学意义（P〈0.05）。结论中医补肾益精法联合西医疗法可以有效治疗少弱畸精子综合征患者,具有较为显著的临床疗效。
Objective To analyze the clinical efficacy of TCM Bushenyijing method combined with western medicine treatment of oligo-asteno-teratozoospermia syndrome. Methods Total of 160 oligo-astenoteratozoospermia syndrome patients in Zhengzhou Hospital of Traditional Chinese Medicine from Dec. 2013 to Dec. 2014 were included in the study and divided into trial group and control group according to random number table method,80 cases each. The control group was treated with FSH and h CG,FSH 75 U,3 times /week; h CG 4000 U,1 time / week. The trial group was treated by zengjingwan 6 g / time,3 times / day on the basis of the control group’s treatment. 3 months as a course of treatment,all the patients were treatment for a course. The sperm and serum sex hormone of the two groups were observed and compared. Results After treatment sperm density,survival rate and（ a ＋ b） level of sperm percentage of the trial group were significantly higher than the control group[（ 49 ± 12） × 10~9/ L vs（ 42 ± 11） × 10~9/ L,（ 48 ± 12） % vs（ 43 ±12） %,（ 64 ± 12） % vs（ 56 ± 13） % ],abnormal rate was significantly lower than the control group [（ 22 ±4） % vs（ 26 ± 6） %]. After treatment,the FSH,LH,T levels of the trial group were significantly higher than those in the control group[（ 14. 8 ± 1. 9） U / L vs（ 12. 6 ± 1. 7） U / L,（ 48. 6 ± 12. 1） U / L vs（ 6. 9 ±1. 4） U / L,（ 21 ± 3） U / L vs（ 19 ± 3） U / L]（ P 〈 0. 05）. The green fluorescent sperm percentage of the trial group was significantly higher than the control group [（ 69 ± 12） % vs（ 62 ± 13） % ],red fluorescent sperm percentage was significantly lower than the control group[（ 16 ± 5） % vs（ 22 ± 7） % ]（ P 〈 0. 05）.Conclusion TCM Bushenyijing method combined with western medicine can effectively treat oligo-astenoteratozoospermia syndrome,with significant clinical efficacy.
出处
《医学综述》
2016年第7期1379-1381,共3页
Medical Recapitulate
关键词
少弱畸精子综合征
性激素
补肾益精法
中医疗法
Oligo-asteno-teratozoospermia syndrome
Sex hormone
Bushenyijing method
Traditional Chinese medicine
