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新疆巴州地区不同民族散发型乳腺癌组织中VEGF的表达及其临床病理意义

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摘要 目的:探讨血管内皮细胞生长因子(VEGF)在新疆巴州地区维吾尔族(维族)、汉族、蒙古族(蒙族)、哈萨克族(哈族)和回族妇女散发型乳腺癌组织中的表达及其与临床病理特征的关系和意义。方法采用免疫组化法检测103例维族、汉族、蒙族、哈族和回族妇女乳腺浸润癌中VEGF的表达,分析各组间表达的差异及其与临床病理参数的关系。结果:不同民族散发型乳腺癌组织中VEGF的阳性率分别是,维族:72.73%(24/33);汉族76.92%(20/26);蒙族71.43%(15/21);哈族77.78%(7/9);回族71.43%(10/14),各民族间VEGF阳性率差异无统计学意义(P>0.05)。在维族、汉族、蒙族妇女散发型乳腺癌组织中VEGF表达与淋巴结转移、临床分期、病理类型有关,与患者年龄、肿瘤直径无关;在回族,VEGF表达与淋巴结转移、临床分期有关,与患者年龄、肿瘤直径、病理类型无关;哈族中,VEGF表达与患者年龄、肿瘤直径、淋巴结转移、临床分期、病理类型均无关。结论 VEGF的表达与维族、汉族、蒙族、哈族和回族妇女散发性乳腺癌的发生发展密切相关,检测VEGF表达将有助于判断乳腺癌的转移潜能、血管生成能力及预后。
作者 温实
出处 《兵团医学》 2015年第1期4-6,共3页 Journal of BingTuan Medicine
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参考文献6

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