摘要
目的探讨超声引导下囊内注射甲氨蝶呤（MTX）联合米非司酮口服治疗疤痕子宫切口妊娠的疗效。方法整群选取2013年1月—2015年6月间南通和美家妇产科医院妇产科收治的34例疤痕子宫切口妊娠患者作为研究对象,按数字表示法随机分成观察组和对照组;对照组予以超声引导下囊内注射甲氨蝶呤MTX,对照组在其基础上联合米非司酮口服;比较两组的β-HCG恢复速度、阴道出血量和保守治疗成功率。结果两组在1、2周的β-HCG,β-HCG正常时间和阴道出血量比较,t值分别为2.429、2.374、3.718和2.751,差异有统计学意义（P〈0.05）;在保守治疗成功率比较,χ^2值为9.28,差异有统计学意义（P〈0.05）。结论采用超声引导下囊内注射MTX联合米非司酮口服治疗疤痕子宫切口妊娠,能显著加快β-HCG恢复正常,有效终止妊娠,降低手术率。
Objective To discuss the curative effect of injection of MTX into cyst combined with oral administration of mifepristone guided by ultrasound in treatment of cesarean scar pregnancy. Methods 34 cases of patients with cesarean scar pregnancy treated in the obstetrics and gynecology department of Nantong Hemeijia Obstetrics and Gynecology Hospital from January 2013 to June 2015 were selected as the research object and randomly divided into two groups, the control group were treated with injection of MTX into cyst guided by ultrasound, the observation group were treated with injection of MTX into cyst and oral administration of mifepristone, the recovery rate of β-HCG, vaginal bleeding volume and success rate of conservative treatment of the two groups were compared. Results The differences in the normal time of β-HCG in the first week and the second week and vaginal bleeding volume between the two groups were obvious（t = 2.429, 2.374,3.718 and 2.751）（P〈0.05）, the difference in the success rate of conservative treatment between the two groups was obvious（χ~2= 9.28）,（P0.05）. Conclusion Injection of MTX into cyst combined with oral administration of mifepristone guided by ultrasound in treatment of cesarean scar pregnancy can obviously accelerate β-HCG to return to normal, effectively terminate pregnancy and reduce the operative rate.
出处
《中外医疗》
2016年第7期96-97,100,共3页
China & Foreign Medical Treatment
关键词
疤痕子宫妊娠
超声
MTX
米非司酮
疗效
Cesarean scar pregnancy
Ultrasound
MTX
Mifepristone
Curative effect
