摘要
目的：研究印尼仙人冠果-积雪草口服液＂JAMKHO＂（由印尼Mahkotadewa Indonesia有限公司生产;印尼食品药品管理局注册号：TR 133672511）对患者随时血总胆固醇浓度之即刻影响。方法：本研究设计为对服用仙人冠果-积雪草口服液＂JAMKHO＂前和服用后的患者血总胆固醇浓度差异进行评价。检测患者临时血总胆固醇浓度在服用JAMKHO口服液前及服用后1 h,所获得的配对血总胆固醇浓度数据按统计学双侧t检验分析差异并总结,统计学意义界限α为0.05。结果：在2014年11月和12月来诊所的患者中获得41位同意成为本研究对象,其中女性21人和男性20人,患者年龄18~76岁,平均（45.66±14.03）岁。患者的平均微血管血血总胆固醇浓度在服用JAMKHO口服液前是（232.98±37.02）mg/d L,而服用后1 h是（194.12±34.85）mg/d L,差异具有统计学意义（P〈0.01）。而在服用JAMKHO前血总胆固醇浓度低于200 mg/d L的患者中（n=8）,其服用JAMKHO后的血总胆固醇浓度变化无统计学意义（P〉0.05）。结论：印尼仙人冠果-积雪草口服液＂JAMKHO＂能有效地在1 h内降低患者的血总胆固醇浓度（P〈0.01）,尤其在服用前血总胆固醇浓度200 mg/d L以上者.然而在服用JAMKHO前血总胆固醇浓度低于200 mg/d L的患者,服用JAMKHO后的血总胆固醇浓度无明显变化（P〉0.05）。
Objective： To study the immediate effect of Indonesian herbal solution Jamkho upon total blood cholesterol level.Methods： Subjects were clients / patients of a traditional medicine clinic in Jakarta who had agreed to be tested their random blood cholesterol levels pre and one hour post ingestion of two spoonful of herbal solution Jamkho. The pre and post ingestion data were analyzed using paired t-test. Results： There were 41 subjects included,consisting of 21 female and 20 male,with an average of（ 45. 66 ± 14. 03） years old. Their average random blood total cholesterol level before given Jamkho was（ 232. 98 ± 37. 02） mg/d L,and after given Jamkho was（ 194. 12 ± 34. 85） mg / d L. The difference was highly significant（ P 〈 0. 01）,while subgroup with initial blood total cholesterol levels below 200 mg / d L did not show significant changes of blood total cholesterol level（ P 〉 0.05） after ingestion of Jamkho. Conclusion： The herbal solution Jamkho could effectively lower random blood total cholesterol levels very significantly（ P 〈 0. 01） upon subjects studied,especially those with initial total blood cholesterol levels 200 mg / d L and above. But upon subjects with initial blood total cholesterol levels below 200 mg / d L,Jamkho did not change the levels significantly（ P 〉 0. 05）.
出处
《世界中医药》
CAS
2016年第2期236-238,243,共4页
World Chinese Medicine
