摘要
人可溶性髓系细胞触发受体1（sTREM-1）是新近发现的与炎症反应密切相关的免疫球蛋白家族成员，是炎症反应的敏感标记物，多种病原微生物感染均能使sTREM-1高度表达，其通过TOLL样受体作用，参与促炎因子的分泌，在脓毒症发生发展过程中扮演着重要角色，是近年来脓毒症诊断及病情监测中较为敏感可靠的新指标。因此有必要研究sTREM-1在脓毒症病程发生发展中的特点及作用，对预防脓毒症的发生及合理治疗、病情预后评估等方面具有重要意义。
The Strem-1 is a member of the immunoglobulin family, which is recently found to be closely associated with the inflammatory and a sensitive marker of the inflammatory response. Many pathogenic microorganisms infection can make sTREM-1 highly expressed, it is involved in the secretion of pro-inflammatory factors by the role of TOLL receptors, and played an important role in the development of sepsis. It is a moresensitive and reliable indicator in the diagnosis and monitoring of sepsis in recent years. It is necessary to study the characteristics and role of sTREM-1 in the development of sepsis, and it has important significance in preventing the occurrence of sepsis and reasonable treatment or prognosis evaluation.
出处
《中国综合临床》
2016年第3期279-281,共3页
Clinical Medicine of China
