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二甲双胍及饮食干预改善多囊卵巢综合征孕妇妊娠结局的效果 被引量：10

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摘要 目的探讨二甲双胍联合饮食干预对多囊卵巢综合征(POCS)孕妇妊娠结局的改善效果。方法 PCOS患者173例,采用随机数字表法分为干预组83例和对照组90例。对照组在妊娠前口服炔雌醇醋酸环丙孕酮片(1片/d,连服21 d),停药后待撤退出血第5天起重复用药。疗程3个月,3个月后监测排卵,指导受孕。受孕后,行常规饮食及健康教育。干预组采用与对照组相同的方法助孕,此外,采用二甲双胍联合饮食控制干预。比较两组妊娠结局(活产数、流产数)、妊娠期糖尿病发病率、子痫前期、孕周数、新生儿出生体重。结果干预组流产与活产分别为17例(20.5%)与66例(79.5%),对照组分别为35例(38.9%)与55例(61.1%),干预组活产率明显高于对照组(P<0.05)。两组妊娠期糖尿病和子痫前期发生率、孕周、新生儿出生体重比较,差异均无统计学意义(P均>0.05)。结论在孕前及孕中给予PCOS孕妇二甲双胍及饮食干预,可明显改善其妊娠结局,提高活产率。
作者 莫紫文 张应亮
机构地区 广西南宁市第九人民医院妇科
出处 《广西医学》 CAS 2016年第3期413-415,共3页 Guangxi Medical Journal
关键词 多囊卵巢综合征 妊娠 二甲双胍 饮食控制 妊娠结局
分类号 R714.2 [医药卫生—妇产科学]
  • 相关文献

参考文献11

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二级参考文献24

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广西医学
2016年 第3期

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