摘要
目的:探讨灼口综合征(BMS)患者的口干症状与焦虑和抑郁症状的关系。方法:按照病例对照研究的方法,选取某口腔医院口腔黏膜科就诊的BMS患者147名为病例组,并将其分为BMS伴口干者(n=64)和BMS不伴口干者(n=83)两个病例组;选取与BMS患者年龄匹配的非BMS患者147名为对照组。使用焦虑自量表(SAS)、抑郁自评量表(SDS)评估三组患者的焦虑和抑郁症状,采用logistic回归进行危险因素分析。结果:BM S病例组中,口干检出率为43.54%。BM S伴口干病例组SAS、SDS标准分均高于对照组(P<0.01)。伴口干症状BM S的危险因素为女性(OR=4.17)、中度和重度焦虑症状(OR=12.04)。在BMS病例中发生口干症状的危险因素为疼痛程度高(OR=1.43)、空腹血糖高(OR=3.44)。结论:女性和中到重度焦虑症状对BMS口干症状的发生有关联作用,BMS患者口干症状的发生与疼痛程度较重、空腹血糖水平较高相关联。
Objective: To explore the relation of xerostomia to anxiety and depression symptoms in patients w ith burning mouth syndrome( BM S). Methods: A case-control study w as carried out in the Department of Oral M edicine of a stomatology hospital. Case group included 147 BM S patients w ho w ere divided into tw o subgroups( 64 patients w ith xerostomia and 83 patients w ithout xerostomia), and control group included 147 non-BM S patients. With the Self-Rating Anxiety Scale( SAS) and Self-Rating Depression Scale( SDS),the patients' symptoms of anxiety and depression w ere evaluated. Logistics regression w as conducted to explore risk factors. Results: The detectable rate of xerostomia in case group w as 43. 54%. The standard scores of SAS and SDS w ere significantly higher in BM S patients w ith xerostomia than in the control group( P〈0. 01). Risk factors of BM S w ith xerostomia w ere female( OR = 4. 17),moderate and severe anxiety symptom( OR = 12. 04). Among the BM S patients,xerostomia w as associated w ith degree of pain( OR = 1. 43) and fasting plasma glucose( OR = 3. 44). Conclusion: There are association betw een BM S w ith xerostomia and female,moderate and severe anxiety symptom. Risk factors of xerostomia in BM S patients are higher pain and higher fasting plasma glucose.
出处
《中国心理卫生杂志》
CSSCI
CSCD
北大核心
2016年第4期253-257,共5页
Chinese Mental Health Journal
关键词
灼口综合征
口干
焦虑
抑郁
病例对照研究
burning mouth syndrome
xerostomia
anxiety
depression
case-control studies