摘要
目的用MRI评价肝硬化门静脉血栓（Portal vein thrombus,PVT）数量、解剖位置、信号特征及其与Child-Pugh分级的相关性。方法回顾性分析2011年3月~2015年10月经临床随访、CT或超声诊断的肝硬化门静脉血栓（PVT）的住院病人27例,以及同期肝硬化患者中未发生PVT患者222例,所有患者均有门静脉高压表现,均行常规MRI平扫及三维容积超快速多期动态增强扫描（LAVA）,采用MRI观察门静脉血栓的数量、位置、信号特征,并与肝硬化Child-Pugh分级做对照分析。结果肝硬化PVT发生率为10.84%（27/249）。在27例血栓患者中共发现34个血栓,其解剖分布,位于门静脉主干22个,同时累及其左支或右支或者两支9个;位于门静脉右支3个,位于肠系膜上静脉7个,位于脾静脉2个。MRI均能显示门静脉内血栓,血栓在T1WI平扫上呈现两种不同的信号,信号值为（1134.17±35.28）和（291.33±58.20）,分别代表新鲜血栓和陈旧性血栓。血栓的数量、解剖分布、信号强度差异与Child-Pugh分级间的相关性无统计学差异（P〉0.05）。结论 MRI能准确显示肝硬化PVT的数量、解剖部位及新鲜血栓或陈旧血栓。
Objective To explore the features of portal vein thrombosis（PVT）secondary to liver cirrhosis including the number,anatomic distribution and signal intensity on magnetic resonance imaging（MRI）,and determine whether the PVT is associated with Child-Pugh classification.Methods Between March 2011 and October 2015,27 inpatients with liver cirrhosis in our hospital were confirmed by clinical data,and Doppler ultrasonography or computed tomography.During this period,222 cirrhotic patients without PVT were also enrolled in this study to calculate the incidence of PVT.All patients had the clinical appearances of portal hypertension and underwent routine MRI scan and a three-dimensional volume of the ultra-fast multi-phase dynamic contrast-enhanced scans（LAVA）.On MRI,the number,anatomic distribution and signal intensity of PVT were reviewed,and the correlation of the occurrence of PVT with ChildPugh class of cirrhosis was assessed.Results The incidence of PVT in patients with portal hypertension secondary to liver cirrhosis was 10.84%（27/249）.34 thrombi were found in 27 patients,22thrombi were located in the main branch of portal vein including 9thrombi involving the left branch or right branch or the two,3thrombi were located in right branch of portal vein,7thrombi were located in the superior mesenteric vein,and 2thrombi were located in splenic vein.All thrombi in the portal vein were well depicted on MRI.On T1-weighted imaging,thrombus presented as two different signals representing fresh thrombus and old thrombus,and signal intensity was 1134.17±35.28 and 291.33±58.20,respectively.The number,anatomic distribution and signal intensity of PVT on MRI were not correlated with Child-Pugh class of cirrhosis（P〈0.05）.Conclusion MRI can well show the number,anatomic distribution PVT and determine whether it is old or fresh thrombus.
出处
《西部医学》
2016年第4期515-519,共5页
Medical Journal of West China
基金
国家自然科学基金(81050033)
四川省科技支撑计划项目(2011SZ0237)
关键词
门静脉
血栓
肝硬化
磁共振
Portal vein
thrombosis
Liver cirrhosis
Magnetic resonance imaging
