摘要
目的研究长航对女舰员内分泌及免疫功能的影响，为制定长远护航人员身体健康保障措施提供理论依据。方法选取33名女舰员，采用自身对照研究方法，分别于出航前、返航途中及到港3个月后比较内分泌激素：皮质醇（COR）、促甲状腺激素（TSH）、游离T3（FT3）、游离T4（FT4）、泌乳素（PRL）、卵泡刺激素（FSH）、黄体生成素（LH）、雌二醇（E2）及睾酮（T）水平；同时比较体液免疫指标IgA、IgG、IgM、C3、C4水平。结果长航中与长航前比较血清COR升高，FT3降低；血清PRL升高，FSH、LH、E2降低；血清IgG、补体C3降低，差异均有统计学意义（P〈0．05或P〈0．01）。结论长航中女舰员出现慢性应激，对女舰员内分泌、免疫功能有一定程度的影响。因此，加强女舰员长航健康保健十分重要。
Objective To investigate the effects of prolonged deployment at sea on endocrine and immune system of female naval afloat personnel, so as to provide evidence in the development of health protective measures for those naval personnel during their prolonged deployment at sea. Methods A total of 33 female naval afloat personnel were chosen for the study. By using self-control method, the levels of cortisol （COR） , thyroid stimulating hormone （ TSH ） , free T3 （ FT3 ） , free T4 （ FT4 ） , prolactin （ PRL ） , follicle stimulating hormone （FSH）, luteinizing hormone （LH）, estrzdiol （E2） and testosterone （T）, as well as such humoral immune indices of IgA, IgG, IgM, C3 and C4 were detected before deployment, on the way back to the homeport and 3 months after arrival at the homeport. Results During prolonged deployment at sea, changes could be seen in the following indices： the level of COR was increased, while the level of FT3 was decreased ; the levels of PRL were increased, whi^e the leve^s of FSH, LH and E2 were decreased; the ~eve^s of IgG and C3 were also decreased, and statistical significance could be noticed, when comparisons were made between the indices before deployment and those after deployment （ P 〈 0.05, P 〈 0.01 ）. Conclusions During prolonged deployment at sea, females displayed signs of chronic stress, which had certain effect on endocrine and humoral immune functions of the females. For this reason, it was of great importance to improve heahhcare of females during prolonged deployment at sea.
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
2016年第1期27-30,共4页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
基金
海军后勤部“十二五”项目（CHJ11J015）
关键词
长航
女舰员
应激
内分泌
免疫
Prolonged deployment at sea
Female naval afloat personnel
Stress
Endocrine
Immunity
