摘要
目的通过对非高血压居民横断面调查和2年的随访研究,探讨不同睡眠时间与高血压发生的相关性。方法于2011年5月至2012年12月,采用自然抽样法调查天津市内六区年龄在40~70岁的非高血压人群年龄、性别、文化水平等人口学资料及抽烟、饮酒、体育锻炼、睡眠等生活行为特征,并进行身高、体重、腰围等体格检查和血脂、血糖等生化指标检测,2年后对入组人群再次进行体格检查和生化检测,通过多因素logistic分析不同睡眠时间与高血压进展的关系。结果非高血压人群2年后随访,成功回访组和失访组基线资料比较差异无统计学意义（P〉0.05）;与发生高血压组人群相比,非高血压组人群年龄、腰围、体质指数、甘油三酯（TG）、尿酸（UA）、高敏C反应蛋白（hs-CRP）水平低,吸烟、确诊糖尿病比例低,而高密度脂蛋白胆固醇（HDL-C）水平、女性比例、高中及以上学历人群比例高。通过多因素logistic分析发现,40~54.9岁人群中,睡眠时间≤4.9 h的高血压发病风险是睡眠时间7.0~7.9 h的3.15倍,在校正了性别、年龄、腰围、体质指数、TG、HDL-C、LDL-C、UA、hs-CRP、吸烟、饮酒、体育锻炼和确诊糖尿病等因素后仍然具有统计学意义（OR=3.43,95%CI：1.06~11.10）,55~70岁人群中则无统计学意义。结论睡眠时间过少会增加高血压发病风险,且与年龄相关。
Objective To explore the correlation between sleeping duration and hypertension by following-up for 2 years in nonhypertension residents. Methods The data of sociodemographic information（age, sex and education level）, lifestyle（smoking,drinking, physical exercise and sleeping duration） were collected by questionnaires; the height, weight and waist circumference（BMI, WC） and biochemical parameters（blood glucose, blood lipids and serum creatinine） were examined in non-hypertension residents（40-70 years old）. After following up for 2 years, above examinations were performed again. The multivariate logistic regression was used to analyze the correlation between sleeping duration and hypertension. Results After following-up for 2 years,there were no significant differences of baseline data between the return visit group and the loss of access group. As compared with hypertension subgroup, the age, waist circumference, BMI, TG, UA, hs-CPR, smoking rate and diabetes rate decreased, and the serum HDL-C level, the female proportion and higher education level rate（≥high school level） increased in non- hypertension subgroup. The multivariate logistic regression showed that in younger group（ 40- 54. 9 years old）, the risk of hypertension in residents with less sleeping duration（≤4.9 h） increased 3.15 folds, as compared to the residents with normal sleeping duration（7.0-7.9 h）, there was significant difference of hypertension risk between less sleeping duration subgroup and normal sleeping duration subgroup after adjusting sex, age, WC, BMI, TG, TC, LDL-C, HDL-C, UA, hs-CRP, smoking, drinking, physical activity and diabetes（ OR = 3. 43, 95 % CI ： 1. 06- 11. 10）; but there was no significant difference in elder group（ 55- 70 years old）.Conclusion The less sleeping duration may increase the risk of hypertension, which is related to age.
出处
《中国慢性病预防与控制》
CAS
2016年第4期255-258,共4页
Chinese Journal of Prevention and Control of Chronic Diseases
基金
天津市卫生局科技基金项目(11KG113)
关键词
睡眠时间
高血压
年龄
Sleeping duration
Hypertension
Age
