摘要
目的探讨颅内压(ICP)监测对重度脑室出血脑室-腰大池序贯引流的指导作用及对预后判断的意义。方法 88例重度脑室出血病人均行脑室-腰大池序贯引流治疗,根据是否实施ICP监测分为ICP监侧组(48例)和常规引流组(40例),比较两组治疗结果。结果 ICP监测组人均甘露醇使用总量及电解质紊乱、肾功能损害、应激性溃疡等并发症发生率均显著低于常规引流组(P<0.05),而术后恢复良好率明显高于常规引流组(P<0.05)。两组脑室积血清除情况、病死率及颅内再出血、肺部感染、颅内感染、脑积水等并发症发生率差异无统计学意义(P>0.05)。结论 ICP监测指导下脑室-腰大池序贯引流治疗重度脑室出血有利于早期发现病情变化,避免引流过度或引流不足,减少使用脱水剂,降低相关并发症发生率,改善病人的生存质量。
Objective To explore the guiding role and prognostic prediction significance of intracranial pressure（ICP） monitoring for patients with severe intraventricular hemorrhage undergoing sequential ventricular-lumbar cistern drainage. Methods Eighty-eight patients undergoing sequential ventricular-lumbar cistern drainage for severe intraventricular hemorrhage were divided into ICP monitoring group（48 patients） with ICP monitoring and conventional drainage group（40 patients） without ICP monitoring. The therapeutic outcomes were compared between the two groups. Results The average total dose of mannitol and incidence of electrolyte disturbances, renal function injury, stress ulcer in ICP monitoring group were significantly lower than those in conventional drainage group（P〈0.05）, however, the good recovery rate in ICP monitoring group was superior to that in conventional drainage group（P〈0.05）. There was no significant difference in the evacuation rate of intraventricular hematoma, mortality rate and the incidence of intracranial rehemorrhage, pulmonary infection, intracranial infection and hydrocephalus between the two groups（P〉0.05）.Conclusion Sequential ventricular-lumbar cistern drainage guided by ICP monitoring is beneficial to discover disease change timely,avert excessive or inadequate drainage, and reduce the dosage of dehydrant and associated complications, and improve the life quality of patients.
出处
《中国微侵袭神经外科杂志》
CAS
2016年第3期112-115,共4页
Chinese Journal of Minimally Invasive Neurosurgery
基金
广东省清远市科技计划医疗卫生领域项目(编号:2014B138)
关键词
颅内出血
颅内压监测
引流术
脑室外
引流术
腰大池
intracranial hemorrhage
ICP monitoring
drainage
external ventricular
drainage
lumbar cistern
