摘要
目的:为临床药师融入临床实现个体化用药提供思路。方法:分享临床药师对1例环孢素治疗大疱性类天疱疮患者的药学监护,为患者提供个体化用药方案的成功案例。结果:医师接受建议,调整环孢素用药方案,治疗4日后少见新发红斑水疱,症状改善明显,同时临床药师对合并用药(糖皮质激素、人免疫球蛋白、环孢素等)进行药学监护,未见明显不良反应(adverse drug reaction,ADR),患者好转出院。结论:使用环孢素治疗皮肤系统疾病,监测血药浓度可能具有一定的临床意义,但尚需进一步经过临床实践研究。
OBJECTIVE： To provide ideas for the participation of clinical pharmacists in clinical individualized medication. METHODS： By sharing the pharmaceutical care participated by the clinical pharmacists in the drug therapy of a patient with bullous pemphigoid,the successful example of individualized medication was provided.RESULTS： The clinician accepted the proposal and adjusted the therapeutic regimen. The symptoms of the patient had been improved significantly and new erythema blister were rare after four days of treatment. Meanwhile,the clinical pharmacists provided pharmaceutical care for the drug combination（ corticosteroids,gamma globulin,cyclosporine,etc）, with no significant adverse drug reactions, the patient was discharged with a better health condition.CONCLUSIONS： The application of ciclosporine in treatment of skin diseases and monitor the blood concentration may have clinical significance,yet it still needs to be further researched in clinical practice.
出处
《中国医院用药评价与分析》
2016年第3期423-425,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
大疱性类天疱疮
环孢素
治疗药物监测
临床药师
Bullous pemphigoid
Cyclosporine
Therapeutic drug monitoring
Clinical pharmacists
