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红花黄色素对糖尿病肾病患者炎性反应和蛋白尿的影响 被引量:8

INFLUENCES OF SOFFLOR YELLOW ON INFLAMMATORY REACTION AND PROTEINURIA OF PATIENTS WITH DIABETIC NEPHROPATHY
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摘要 目的:探讨红花黄色素对糖尿病肾病的治疗价值。方法:80例糖尿病肾病患者随机均分为观察组和对照组,对照组采用常规治疗,观察组在常规治疗的基础上加用红花黄色素,均治疗4周。比较两组的疗效、炎性因子水平和蛋白尿情况。结果:观察组的治疗总有效率为87.5%(35/40),明显高于对照组(P<0.05);观察组治疗后的CRP、IL-6、尿总蛋白和UAER均明显低于对照组治疗后(P<0.05);两组均无明显不良反应发生。结论:在常规治疗的基础上加用红花黄色素能够显著改善糖尿病肾病患者的炎性反应水平、降低尿蛋白,提高治疗效果。 Objective: To investigate the therapeutic value for treating diabetic nephropathy with sofflor yellow. Methods: 80 diabetic nephropathy patients were randomly divided into observation group and control group. The patients in control group were treated with conventional therapy; on the basic of conventional therapy, the patients in observation group also took soffl or yellow; all the patients were treated for 4 weeks. The therapeutic effects, level of infl ammatory factors and proteinuria of patients in 2 groups were compared. Results: The total effective rate of observation group was 87.5%(35/40), which was obviously higher than control group(P〈0.05). The CRP, IL-6, 24 h total urine protein and UAER of patients in observation group after treatment were obviously lower than control group(P〈0.05). There had no obvious adverse reactions occurred in 2 groups. Conclusions: Conventional therapy combined soffl or yellow can obviously improve infl ammatory reaction and reduce proteinuria of patients with diabetic nephropathy, so can improve therapeutic effects.
出处 《承德医学院学报》 2016年第3期194-196,共3页 Journal of Chengde Medical University
关键词 红花黄色素 糖尿病肾病 炎性反应 蛋白尿 Saffl or yellow Diabetic nephropathy Infl ammatory reaction Proteinuria
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