摘要
目的:用Meta分析评价血栓抽吸联合替罗非班冠脉给药在急性ST段抬高性心肌梗死患者急诊PCI术中的疗效。方法:系统检索有关血栓抽吸联合替罗非班冠脉给药治疗ST段抬高性心肌梗死的随机对照研究。按照预先制定的纳入和排除标准,采用RevMan 5.3软件进行Meta分析。结果:按照预先制定的纳入和排除标准进行筛选,共纳入18篇随机对照试验,研究分为血栓抽吸联合替罗非班冠脉给药组(联合组)和直接PCI组。联合组与直接PCI组相比具有高的TIMI血流3级、STR发生率和LVEF水平。低的MACEs发生率。出血事件发生率未发现明显差异。结论:血栓抽吸联合替罗非班冠脉给药在急诊PCI术中的应用是安全有效的。
Objective：To evaluate the efficacy of thrombus aspiration combined with intracoronary administration of tirofiban in patients with STEMI with emergency PCI by Meta evaluation method.Methods：A literature search was actualized for relevant trials.The research was divided in two groups,including the thrombus aspiration combined with intracoronary administration of tirofiban group（combination group）and PCI group.Results：Two independent investigators assessment the quality and abstracted data of the included RCTs.18 studies were included in this meta-analysis.The research was divided in two groups,including the thrombus aspiration combined with intracoronary administration of tirofiban group（combination group）and PCI group.The therapy of thrombus aspiration combined with intracoronary administration of tirofiban in patients with STEMI with emergency.The therapy of thrombus aspiration combined with intracoronary administration of tirofiban in patients with STEMI with emergency.No significant difference was observed in bleeding complication.Conclusion：The therapy of thrombus aspiration combined with intracoronary administration of tirofiban in patients with STEMI in emergency PCI is effective and safe.
出处
《甘肃医药》
2016年第4期258-262,共5页
Gansu Medical Journal
基金
甘肃省自然科学基金项目(项目编号:1506RJZA249)
