摘要
目的探索首发精神分裂症患者的精神病未治疗时间(duration of unmedicted psychosis,DUP)的变化规律及其相关因素。方法对首都医科大学附属北京安定医院不同年份(1994、2004和2014年)首次发作的精神分裂症出院患者进行回顾性调查,描述DUP的变化。结果不同年份在首都医科大学附属北京安定医院就诊的精神分裂症首次发作的患者中,2014年就诊患者的DUP显著小于1994年和2004年,但后两者之间差异无统计学意义(P>0.05)。2014年精神分裂症患者的DUP与其阳性与阴性症状量表(Positive and Negative Syndrome Scale,PANSS)减分率呈负相关。结论精神分裂症患者从发病到开始治疗的疾病未治疗时间明显缩短,其中学生、未婚和高学历群体的比例呈增加趋势,显示了我国精神卫生事业的发展和进步。
Objective To explore the trends of change and related factors in duration of untreated psychosis（ DUP） at first-episode of schizophrenia. Methods Retrospective investigation was employed on relieved patients with first-episode of schizophrenia in Beijing Anding Hospital,Capital Medical University from different years（ 1994,2004 and 2014） to explore DUP changes. Results Statistical analyses showed that DUP in patients with first-episode of schizophrenia in 2014 was significantly lower than that in 1994 and 2004.However,there was no significant difference between the latter two groups. Besides,there was a negative correlation between DUP and reduced score rate of Positive and Negative Syndrome Scale（ PANSS） in 2014. Conclusion The DUP was significantly shortened in patients with schizophrenia,in which the proportion of students,unmarried people and well educated population increased,showing the development and progress of mental health system in our country.
出处
《首都医科大学学报》
CAS
北大核心
2016年第2期168-171,共4页
Journal of Capital Medical University
基金
北京市自然科学基金(7152069)
北京市科委首都临床特色应用研究专项(Z151100004015061)~~
关键词
精神分裂症
精神病未治疗时间
阳性与阴性症状量表
schizophrenia
duration of unmedicted psychosis
Positive and Negative Syndrome Scale
