摘要
目的：研究血肌酐（SCr）水平与急性重症胰腺炎（SAP）患者预后的相关性。方法选取2010年3月至2015年9月期间我院收治的80例SAP患者作为研究对象，所有患者均在发病24 h内入院。根据预后将患者分为三组，其中康复组49例，并发症组23例，死亡组8例。比较各组患者的临床资料并对SAP患者预后的危险因素进行分析。结果死亡组不同时刻的APACHEⅡ评分和Scr水平高于并发症组及康复组，差异具有统计学意义（P＜0.05）。入院后，三组患者的APACHEⅡ评分较入院时明显下降（P＜0.05）。各组患者入院1 d的Scr水平高于入院时，差异无统计学意义（P＞0.05）；与入院时相比，并发症组和康复组入院3～7 d的Scr明显下降（P＜0.05）。多元回归分析中，以患者预后为因变量，以临床资料为自变量，结果显示，年龄、SBP、CRP、SCr和APACHEⅡ评分是患者预后的影响因素（P＜0.05）。结论急性重症胰腺炎患者的血肌酐水平与患者的预后具有明显的相关性，血肌酐水平持续增高提示预后不良。
Objective To study the correlation between serum creatinine（SCr） level and the prognosis of patients with early severe acute pancreatitis （SAP）. Methods A total of 80 patients with SAP were chosen as study objects from March 2010 to September 2015 and all of them were hospitalized within 24 hours. Accord-ing to different outcome, patients were divided into three groups： 49 cases in rehabilitation group, 23 cases in complication group and 8 cases in death group. The clinical data of patients were compared among three groups, and the risk factors of prognosis were analyzed. Results In the death group, APACHEⅡscore and SCr level at different time were higher than that in complication group and rehabilitation group, the difference had statistical significance（P〈0.05）. After admission, APACHEⅡscore in all three groups was significantly decreased than before（P〈0.05）. In all three groups, SCr was increased one day after admission, but the dif-ference had no statistical significance（P〉0.05）. The SCr decreased significantly in rehabilitation and compli-cations groups 3~7 days after admission（P〈0.05）. In multiple regression analysis, age, SBP, CRP, SCr and APACHEⅡwere the factors of the prognosis of patients with SAP. Conclusion SCr level was significantly related to the prognosis of patients, and sustained increase of SCr indicated a bad prognosis.
出处
《现代消化及介入诊疗》
2016年第1期50-53,共4页
Modern Interventional Diagnosis and Treatment in Gastroenterology
