摘要
目的:为提高维C银翘片质量标准和改善药品质量提供理论依据。方法:采用2010年版《中国药典》(一部)维C银翘片项下的高效液相色谱法,测定并比较多个厂家维C银翘片中绿原酸、牛蒡苷、维生素C、对乙酰氨基酚、马来酸氯苯那敏的含量。结果:不同厂家维C银翘片中5种成分的含量差异较大。结论:可考虑改进《中国药典》中收载的维C银翘片的含量测定方法;另厂家应注意对该制剂生产工艺的提高和中药材质量的控制。
OBJECTIVE：To improve the quality standard of Vitamin C yinqiao tablet, and to provide a theoretical basis for im- proving the standards and quality of medicines. METHODS：HPLC in Chinese Pharmacopoeia （2010 edition） was conducted to de- termine the content of chlorogenic acid, arctiin, vitamin C, acetaminophen, chlorphenamine maleate in Vitamin C yinqiao tablet from multiple manufacturers. RESULTS ： There were big differences of the 5 components in Vitamin C yinqiao tablet among differ- ent manufacturers. CONCLUSIONS： The content determination method for Vitamin C yinqiao tablet contained in Chinese Pharmaco- poeia remains to be further improved; and the manufacturers should pay attention to the process of production and quality of tradi- tional Chinese medicinal materials of the preparation.
出处
《中国药房》
CAS
北大核心
2016年第12期1680-1683,共4页
China Pharmacy
