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白细胞介素-35的生物活性及其在类风湿关节炎中的研究进展 被引量:3

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摘要 IL-35是近几年发现的新型细胞因子,2007年Collison等和Niedbala等2个研究小组分别在Natu陀和Eur J Immunol发表了有关IL-35的文章,并阐述了其生物功能。随后越来越多的研究证实其在炎症性、肿瘤性、自身免疫病中发挥着重要的作用。且有研究表明,IL-35可抑制关节炎症的进展,阻止关节的破坏,本文就IL-35的生物活性及其在RA中的研究进展作以综述。
出处 《中华风湿病学杂志》 CAS CSCD 北大核心 2016年第4期268-270,共3页 Chinese Journal of Rheumatology
基金 国家自然科学基金(81302587)
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参考文献25

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  • 2Niedbala W, Wei XQ, Cai B, et al. IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Thl7 cells [J]. Eur J Immunol, 2007, 37 (11): 3021-3029. DOI: 10.1002/ eji.200737810.
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二级参考文献37

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