摘要
目的探讨老年过敏性紫癜患者的临床表现、实验室检查、治疗及预后。方法回顾性分析本院收治的42例60～81岁老年过敏性紫癜患者的临床资料。结果42例老年过敏性紫癜患者中，发病高峰为4。7月。皮疹泛发周身23例（54．76％），关节受累7例（16．67％），消化道受累8例（19．05％），肾脏受累28例（66．67％），6～12个月后尿常规检查结果恢复正常为11例（39．29％）。合并感染9例（21．43％），贫血28例（66．67％），低蛋白血症17例（40．48％）。每天予泼尼松20—130mg治疗14例（33．33％）。应用雷公藤多甙片20-60mg治疗3例（7．14％），应用沙利度胺片50-100mg治疗2例（4．76％）。住院10-46d，平均17．35d。结论老年过敏性紫癜患者皮疹易泛发周身，肾脏比关节和消化道更易受累，且不易恢复。患者易合并低蛋白血症，且病程较长，必要时需加用激素及免疫抑制剂等控制病情。
Objective To investigate the clinical manifestations, laboratory examination, therapy and prognosis of the elderly cases with Henoch-Schonlein purpura. Methods To retrospectively analyze the clinical data of 42 cases of 60 - 81 years old elderly hospitalized patients diagnosed as Henoch-SchOnlein purpura. Results Forty-two elderly patients diagnosed as Henoch-Schonlein purpura, the peak months being April to July. The erythema of 23 cases（54. 76% ） developed all over the body. Seven cases （ 16. 67% ） involved in the arthralgia. Eight cases （19.05%） involved in digestive tract symptom. Twenty-eight cases （66. 67% ） involved in purpura kidney. The routine urine test of 11 cases （39. 29% ）restored to normal after 6 N 12 months. The elderly patients, 9 cases （21.43 % ） involved in infection,28 cases （66. 67 % ） involved in anaemia, 17 cases （40. 48 % ） involved in hypoproteinemia. The 42 patients, 14 cases（33.33% ） were treated with prednisone 20 - 130mg/d, 3 cases （7. 14% ） were treated with Lei Gongteng 20 - 60mg/d, 2 cases（4. 76% ） were treated with thalidomide 50 -100mg/d. The hospitalization time was 10 - 46 days, and the mean was 17.35 days. Conclusion The elderly Henoch-Schonlein purpura patients, developed erythema all over the body easily, kidney more susceptible involved than joint and digestive tract, and rehabilitation was difficult. The patients were more frequently complicated with hypoproteinemia. The course of disease was long, and some patients were treated with glucocorticoid, immunosuppressant to control the disease, when necessary.
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2016年第5期475-476,526,共3页
The Chinese Journal of Dermatovenereology
关键词
过敏性紫癜
老年
Henoch-Schonlein purpura
Elderly
