摘要
BackgroundThe 冠的动脉钙(CAC ) 和大动脉的拱门石灰化(AoAC ) 个别地与心血管的疾病和结果被联系。这研究调查了与经历了胸X光检查的 2018 个稳定的咽峡炎病人全部的 angina.MethodsA 在病人为心血管的诊断和结果与 CAC 相结合的 AoAC 的预兆的价值，心脏的多察觉者计算了断层摄影术被跟随在上面四年估计不利事件，它作为心脏的死亡被分类，击，心肌的梗塞，或重复 revascularization 。胸 X 光检查上的 AoAC 的程度从 0 ～ 3 .ResultsDuring 在规模上被分级后续的四年， 620 个病人被冠的 stenting 对待并且 153 (7%) 不利事件发生了。AoAC 的一个更高的等级与一个更高的 CAC 分数被联系。考克斯回归证明 CAC 分数，然而并非 AoAC，与不利事件被联系。在有 CAC 的病人获得 <；400， AoAC 显示出添加剂在检测重要冠的动脉疾病(CAD ) 的预兆的价值。一如果 AoAC 在有类似的 CAC score.ConclusionsAs AoAC 的病人是在场的，不利事件的风险的渐渐的增加被注意强烈不管年龄或性与 CAC 分数被相关， CAD 的小心的评估将在常规胸 X 光上与 AoAC 在病人被要求。
Background The coronary artery calcium （CAC） and aortic arch calcification （AoAC） are individually associated with cardiovascular disease and outcome. This study investigated the predictive value of AoAC combined with CAC for cardiovascular diagnosis and outcome in patients with angina. Methods A total of 2018 stable angina patients who underwent chest X-ray and cardiac multi-detector computed tomography were followed up for four years to assess adverse events, which were categorized as cardiac death, stroke, myocardial infarction, or repeated revascularization. The extent of AoAC on chest X-ray was graded on a scale from 0 to 3. Results During the four years of fol- low-up, 620 patients were treated by coronary stenting and 153 （7%） adverse events occurred. A higher grade of AoAC was associated with a higher CAC score. Cox regression showed that the CAC score, but not AoAC, were associated with adverse events. In patients with CAC score 〈 400, AoAC showed an additive predictive value in detecting significant coronary artery disease （CAD）. A gradual increases in the risk of adverse events were noted if AoAC was present in patients with similar CAC score. Conclusions As AoAC is strongly correlated with the CAC score regardless of age or gender, careful evaluation of CAD would be required in patients with AoAC on conventional chest X-rays.
