摘要
目的探讨低密度脂蛋白/高密度脂蛋白（LDL/HDL）比值与急性缺血性脑卒中患者危险因素的关系及对预后的预测价值。方法检测38例急性缺血性脑卒中住院患者（观察组）及同期体检人员44例（对照组）的血浆LDL、HDL水平,计算LDL/HDL比值并统计其一般资料和危险因素;对所有患者进行常规治疗,检测治疗前后LDL、HDL水平及比值,并进行1-2年的随访。结果观察组LDL/HDL明显高于对照组,治疗后显著降低,但仍明显高于对照组,差异具有统计学意义（均P〈0.05）;Spearman分析显示急性缺血性脑卒中患者LDL/HDL比值与动脉硬化、心脏病、高血压、BMI危险因素及预后均呈正相关性（均P〈0.05）。结论 LDL/HDL比值是急性缺血性脑卒中的独立危险因素,与其预后明显正相关,可用于临床预测。
Objective To investigate the correlation of LDL / HDL ratio to the risk factors of acute ischemic stroke and its implication for prognosis. Method 38 patients of acute ischemic stroke were firstly chosen as the experimental group and 44 healthy people as determined by physical check-up were chosen as the control group of the study. The plasma LDL and HDL levels and the ratio before and after treatment were measured and calculated. Risk factors and prognosis were recorded and follow-ups were conducted for 1-2 years. Correlation between LDH / HDL ratio and risk factors / prognosis were analyzed. Findings Before treatment,the LDL / HDL ratio in the experimental group was significantly higher than that in control group and was reduced significantly after treatment（ P〈0. 05）,yet still higher than that in the control group（ P〈0. 05）. Correlation analysis showed that LDL / HDL ratio was positively correlated with other risk factors and prognosis（ P〈0. 05）. Conclusion LDL / HDL ratio can serve as an independent risk factor that triggers acute ischemic stroke. It has significantly positive correlation with the prognosis.
出处
《健康研究》
CAS
2016年第2期123-125,共3页
Health Research
