摘要
舍格伦综合征(SS)属于腺体功能受损性自身免疫性疾病,口干症是其首要症状,发病机制不明,尚无有效的治疗方法。水通道蛋白、瞬时受体电位香草酸和舒血管肠肽与SS口干症发病密切相关,本文就三者与SS间的关系等研究进展作一综述。
Sjgren syndrome（SS） is a chronic autoimmune disease that occurs because of the impairment of the exocrine gland function. Xerostomia is the first sign of SS, and this symptom indicates the beginning of lesions. As the pathogenesis remains unclear, no complete treatment exists. Recently, the functions of aquaporins, capsaicin receptor, and vasoactive intestinal peptide in the pathogenesis of SS xerostomia have gradually received increasing attention. Therefore, this paper reviews the functions and treatment of these factors in the pathogenesis of SS xerostomia.
出处
《国际口腔医学杂志》
CAS
北大核心
2016年第3期314-317,共4页
International Journal of Stomatology
基金
山西省科技攻关项目(20150313010-3)~~
关键词
舍格伦综合征
口干症
水通道蛋白
瞬时受体电位香草酸
舒血管肠肽
Sjgren syndrome
xerostomia
aquaporin
transient receptor potential vanillic
vasoactive intestinal peptide
