摘要
目的探讨Ki-67、p53和EGFR、CD117在三阴性乳腺癌组织中的表达及临床意义。方法选取我院在2014年12月~2015年12月收治的31例三阴性乳腺癌患者,将其作为观察组,再选取同期的31例非三阴性乳腺癌患者作为对照组,并进行Ki-67、p53和VEGF、CD117的表达分析。结果观察组在Ki67、p53、EGFR、CD117方面的阳性表达为79.0%、87.1%、83.9%、85.5%,对照组为33.9%、14.5%、21.0%、22.6%;两组比较差异有统计学意义（P〈0.05）。结论 Ki-67、p53和VEGF、CD117对三阴性乳腺癌的恶性程度指标具有现实意义。
Objective Discussion Ki-67, p53 and EGFR, CD117 expression and clinical significance in triple-negative breast cancer. Methods 31 cases with triple negative breast cancer patients were treated in our hospital from December 2014 to December 2015, which is observed as a group, and then select the same period 31 cases of non-triple negative breast cancer patients as a control group, and Ki-67, p53 and VEGF, CD117 expression analysis. Results Observation group Ki67, p53, EGFR, positive expression of CD117 aspect of 79.0%, 87.1%, 83.9%, 85.5%, the control group was 33.9%, 14.5%, 21.0%, 22.6%, the difference was significant（P0.05）. Conclusion Ki-67, p53 and VEGF, the degree of malignancy index CD117 triple negative breast cancer have a real significant value.
出处
《中国继续医学教育》
2016年第9期30-31,共2页
China Continuing Medical Education
基金
河南省医学科技攻关计划项目(编号2011020159)
