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鼻胆管引流术在预防ERCP术后并发症中的意义及其引流时间的研究 被引量:28

Investigation on meaning of endoscopic nasobiliary drainage in prevention of post-ERCP complications and drainage time
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摘要 目的探讨鼻胆管引流术在预防内镜逆行胰胆管造影(ERCP)术后并发症中的意义及其引流时间。方法回顾分析2004-2014年该院2856例成功行ERCP患者,其中ERCP术后未安置鼻胆管引流954例为对照组,ERCP术后安置鼻胆管引流1902例分为常规安置鼻胆管1663例(常规组)和胰腺炎或胆管炎安置鼻胆管239例(炎症组)。结果常规组与对照组ER-CP术后高淀粉酶血症的发生率分别为19.18%(319例)、48.00%(458例),胰腺炎的发生率为2.76%(46例)、8.38%(80例),胆管炎的发生率分别为1.02%(17例)、4.61%(44例),差异均有统计学意义(P〈0.05)。常规组与炎症组白细胞计数、总胆红素基本恢复正常的引流时间分别为3、5d。结论经内经鼻胆管引流术能有效预防ERCP术后并发症,同时推荐ERCP术后安置鼻胆管3~5d。 Objective To investigate the meaning of endoscopic nasobiliary drainage(ENBD) in the prevention of post-ERCP complications and the drainage time. Methods Totally 2 856 cases of ERCP in our hospital from 2004 to 2014,including 1 902 cases of ENBD and 954 cases of non-ENBD,were analyzed. Meanwhile the 1 902 cases of ENBD were divided into 1 663 cases of conven- tional nasobiliary drainage(conventional group) and 239 cases of nasobiliary drainage due to preoperatively diagnosed pancreatitis or cholangitis( inflammation group). Results The incidence rates of hyperamylasemia in the conventional group was significantly lower than that in the control group(19.18% vs. 48.00% ,P〈0. 05;2. 76% vs. 8.38% ,P〈0.05). The incidence rates of pancreatitis were 2.76%(46 cases) and 8.38% (80 cases) ;the incidence rates of cholangitis were 1.02%(17 cases) and 4.61%(44 cases) ,and the differences were statistically significant(P〈0.05). The drainage time of WBC and TBil basically recovering to normal level was 3 d in the conventional group and 5 d in the inflammation group. Conclusion The endoscopic nasobiliary drainage can effectively prevent post-ERCP complications. Meanwhile it is recommended that the nasobiliary drainage is conducted for 3-5 d after ERCP. [-
出处 《重庆医学》 CAS 北大核心 2016年第13期1801-1802,1859,共3页 Chongqing medicine
关键词 胰胆管造影术 内窥镜逆行 鼻胆管引流 高淀粉酶血症 胰腺炎 胆管炎 cholangiopancreatography, endoscopic retrograde endoscopic nasobiliary drainage hyperamylasemia pancreatitis cholangitis
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