摘要
目的:比较几种抗甲真菌药物单用或联合用药治疗的临床效果。方法:对212例确诊为甲真菌病的患者,分别给予单用药5%阿莫罗芬甲搽剂(D组)、伊曲康唑(E组)、特比萘芬(F组)以及联合用药即5%阿莫罗芬甲搽剂联合特比萘芬(A组)、5%阿莫罗芬甲搽剂联合伊曲康唑(B组)、特比萘芬联合伊曲康唑(C组)治疗,比较治疗后各组的临床疗效、真菌学治愈率、复发率。结果:C组临床有效率明显优于E、F组,A、B组的真菌学治愈率最高,A组复发率最低,组间比较差异均有统计学意义(P<0.05)。结论:5%阿莫罗芬甲搽剂+特比萘芬联合用药可为临床治疗甲真菌病首选抗菌方案。
Objective：To compare the clinical effect of several kinds of antifungal single drug or combination in the treatment of onychomycosis.Method：212 patients with onychomycosis were divided into 6 groups,5% Amorolfine Hyhloride Liniment（group D）, Itraconazole（group E）, Terbinafine（group F） or combination with 5% Amorolfine hyhloride liniment joint Terbinafine（group A）, 5% Amorolfine Hyhloride Liniment joint Itraconazole（group B） and Terbinafine joint Itraconazole（group C）.After treatment,the rate of clinical efficacy,mycology cure and recurrence of all groups were compared. Result：The clinical efficacy in group C was obviously better than that of group E and group F,the mycology cure rate in the group A and group B were the highest,relapse rates in the group A were the lowest,compared the groups of that,the differences were statistically significant（P〈0.05）.Conclusion：5% Amorolfine Hyhloride Liniment joint Terbinafine combination could be a preferred antibacterial solution for the clinical treatment of onychomycosis.
出处
《中国医学创新》
CAS
2016年第13期24-26,共3页
Medical Innovation of China
基金
东莞市医疗卫生科技计划一般项目(2014105101040)
关键词
阿莫罗芬甲搽剂
伊曲康唑
特比萘芬
甲真菌病
临床疗效
5% Amorolfine Hyhloride Liniment
Terbinafine
Itraconazole
Onychomycosis
Clinical efficacy
