摘要
目的观察炎琥宁注射液用于治疗小儿支气管肺炎的临床疗效及安全性。方法选取小儿支气管肺炎患者102例为研究对象,将患者按随机数字表法分为观察组和对照组,各51例,对照组给予常规治疗,观察组在对照组治疗基础上加用炎琥宁注射液治疗,比较两组患者治疗后的临床疗效、各项临床症状体征消失时间及药物不良反应发生情况。结果观察组治疗后治愈、好转、无效例数分别为27例、23例、1例,总有效率为98.04%;对照组分别为18例、25例、8例,总有效率为84.31%。观察组总有效率明显高于对照组,差异有统计学意义（χ2=5.97,P〈0.05）。观察组咳痰喘、肺部阴影、肺部啰音及发热时间分别为（5.19±2.31）d、（6.00±1.86）d、（5.16±1.51）d、（2.07±0.85）d,均明显短于对照组,差异均有统计学意义（t=4.23、5.01、3.95、3.84,均P〈0.05）。观察组药物不良反应发生率为25.49%,与对照组的药物不良反应发生率相当,差异无统计学意义（P〉0.05）。结论炎琥宁注射液用于小儿支气管肺炎可明显提高临床疗效,缩短各项临床症状体征消失时间,疗效可靠,安全性较高。
Objective To study the clinical efficacy and safety of Yanhuning injection in the treatment ofbronchial pneumonia in children. Methods 102 cases of bronchial pneumonia were randomly divided into theobservation group and the control group, 51 cases in each group. The control group was given conventional treatment,the observation group was given Yanhuning injection on the basis of the treatment of control group. The clinical efficacyafter treatment, clinical symptoms and signs disappeared time and adverse drug reaction were compared between thetwo groups. Results In the observation group after treatment, the cured, improvement, invalid cases were 27 cases,23 cases, 1 case, the total effective rate was 98. 04%, which in the control group were 18 cases, 25 cases, 8 cases, thetotal effective rate was 84. 31%. The total effective rate of the observation group was significantly higher than that ofthe control group （ χ 2 =5. 97, P 〈0. 05） . The cough asthma, shadows in the lungs, pulmonary rales and heating timein the observation group were （ 5. 19 ± 2. 31） days, （ 6. 00 ± 1. 86） days, （ 5. 16 ± 1. 51） days, （ 2. 07 ± 0. 85） days,which were significantly shorter than those of the control group, the differences were statistically significant （ t =4. 23,5. 01, 3. 95, 384, all P 〈0. 05） . The incidence rate of adverse drug reactions in the observation group was 25. 49%,and the difference was not statistically significant compared with the control group （ P 〉 0. 05） . Conclusion Yanhuning injection for the treatment of children with bronchial pneumonia can significantly improve the clinical curativeeffect, shorten the disappearance time of the clinical symptoms and signs, the curative effect is reliable, high security.
出处
《中国基层医药》
CAS
2016年第9期1401-1404,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
支气管肺炎
炎琥宁
儿童
Bronchial pneumonia
Yanhuning injection
Children
