摘要
目的探讨妊娠合并甲状腺功能亢进症控制状态对妊娠结局的影响。方法选取本院2013年1月～2015年12月收治的226例甲状腺功能亢进症孕妇作为研究对象,根据孕妇意愿分为对照组（96例）和观察组（130例）。对照组不采取任何干预措施,观察组给予甲巯咪唑片口服。比较两组的妊娠结局及新生儿甲状腺激素水平。结果观察组的产后出血量显著少于对照组,新生儿Apgar评分显著高于对照组,差异有统计学意义（P〈0.05）。观察组的产褥感染率为5.38%,显著低于对照组的17.71%,差异有统计学意义（P=0.003）。观察组的新生儿T_3、T_4、FT_3、FT_4、TSH水平显著低于对照组,差异有统计学意义（P〈0.05）。结论监测妊娠早期甲状腺功能、早期进行干预有助于改善妊娠结局,且对患者及胎儿无明显副作用,值得临床推广应用。
Objective To explore the influence of controlling state of pregnancy complicated with hyperthyroidism on pregnancy outcome. Methods 113 pregnant women with hyperthyroidism in our hospital from January 2014 to June2015 were selected and divided into the control group（48 cases） and the oberservation group（65 cases） according to the wishes of the pregnant women.The control group was not given intervention measure,the treatment group was treated with oral methimazole tablets.The pregnancy outcome and neonatal thyroid hormone level of the two groups was compared. Results The amount of postpartum hemorrhage in the observation group was less than that in the control group,the neonatal Apgar score in the observation group was higher than that in the control group,with significant difference（P〈0.05）.The puerperal infection rate of the observation group was 5.38%,which was lower than 17.71% of the control group,with significant difference（P=0.003）.The level of T_3,T_4,FT_3,FT_4 and TSH of newborn in the observation group was lower than that in the control group,with significant difference（P〈0.05）. Conclusion Monitoring early pregnancy thyroid function,early intervention is helpful to improve pregnancy outcome,and no significant side effects on the patients and the fetus,it is worthy of clinical promotion and application.
出处
《中国当代医药》
2016年第10期111-113,共3页
China Modern Medicine
