摘要
目的观察还少丹用于治疗脑动脉硬化轻度认知障碍患者的临床效果。方法收集2011年12月—2014年12月期间收治的114例脑动脉硬化导致的轻度认知障碍患者的临床资料,根据入院顺序随机将114例患者分为观察组(n=57)和对照组(n=57),对照组采用西医西药治疗方案,观察组在对照组治疗基础上加用还少丹并辨证加减治疗,观察2组患者治疗效果,统计两组患者治疗前后长谷川痴呆量表(HDS)评分和简易智能量表(MMSE)评分,评价治疗疗效。结果经过4周连续治疗,2组患者HDS评分及MMSE评分均有明显改善,但观察组患者改善程度明显优于对照组,差异存在统计统计学意义(P<0.05);观察组患者治疗有效率为91.2%,对照组为73.7%,二者相比,差异亦存在统计学意义(P<0.05)。结论在常规西医治疗基础上加用还少丹加减治疗因脑动脉硬化导致的轻度认知障碍患者,能有效改善患者临床症状,改善患者预后,提高患者日常生活能力,值得临床推广应用。
Objective To observe the clinical effect of Huanshao Dan in the treatment of mild cognitive impairment of patients with cerebralarteriosclerosis. Methods Patients（114 cases） with mild cognitive impairment in hospital from December 2012 to Decem-ber 2014 were randomly divided into control and treatment groups, and each group had 57 cases. Patients in the control group were treated by conventional medicines. Patients in the treatment group were treated by Huanshao Dan on the basis of control group. The scores of Hasegawa dementia scale（HDS） and mini-mental state examination（MMSE） before and after treatment were compared between the two groups, and then the curative effect was evaluated. Results The MMSE score and HDS score of both groups were obviously improved, and the indexes of the treatment group were higher than those of the control group（ P〈0.05）. The total effective rate of the control group was 73.7%, total effective rate of the treatment group was 91.2%, and the difference was statistically significant（P〈0.05）. Conclusion Huanshao Dan combined with conventional medicines has curative effect in the treatment of mild cog-nitive impairment could improve clinical symptom, enhance activity of daily living, which has a certain clinical application value.
出处
《中国中医药现代远程教育》
2016年第8期87-88,共2页
Chinese Medicine Modern Distance Education of China
关键词
还少丹
脑动脉硬化
轻度认知障碍
健忘
Huanshao Dan
cerebralarteriosclerosis
mild cognitive impairment
amnesia
